From: Decreased serum MMP-9 levels in patients with nontraumatic osteonecrosis of the femoral head
 | ONFH patients (n = 102) | Healthy controls (n = 97) | P value |
---|---|---|---|
Age (Y) | 45.45 ± 10.15 | 43.21 ± 9.49 | 0.109 |
Sex (F/M) | 60/42 | 56/41 | 0.876 |
BMI (kg/m2) | 24.15 ± 3.38 | 23.79 ± 2.80 | 0.411 |
Disease duration (M) | 29(3–136) | / |  |
VAS scores | 4.79 ± 2.08 | / |  |
HHS scores | 61.93 ± 16.77 | / |  |
FICAT stage (1/2/3/4) | 13/24/33/32 | / | Â |
alcohol/Steroid/idiopathic (n) | 41/26/35 | / | Â |
MMP-9 level (ng/ml) | 1073.26 ± 564.34 | 587.84 ± 295.70 |  < 0.05 |
TIMP-1level (ng/ml) | 186.52 ± 71.87 | 207.81 ± 85.34 | 0.058 |
MMP-9/TIMP ratio | 7.17 ± 6.71 | 3.07 ± 1.48 |  < 0.05 |