Fig. 2
From: Exposure to oxLDL impairs TGF-β activity in human tendon cells
oxLDL changes the expression of collagen and the factors that mediate matrix remodeling. Exposure of human tendon cells to progressively increasing doses of oxLDL resulted in reduction of key mRNAs involved in anabolic processes such as COL1A1, COL1A2, COL3A1, DCN, ILK, ITGB1, and LOX. Conversely, the expression of specific MMPs (MMP1, MMP3, and MMP14) were increased. Mean ± SE; * P ≤ 0.05; **P ≤ 0.01; ***P ≤ 0.001; ****P ≤ 0.0001; n = 4 biological replicates