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Table 3 Results of subgroup analysis of included trials in meta-analysis

From: Effect of nanoparticles on gouty arthritis: a systematic review and meta-analysis

Groups

n

Allopurinol

n

The model group

WMD (95%CI)

P-value

I2

WMD (95%CI)

P-value

I2

Material

 Metal

3

0.382(-0.358, 1.121)

0.312

0.00%

3

-7.414(-8.563, -6.264)

0.000

0.00%

 Non-metal

6

-0.257(-0.489, -0.024)

0.030

52.90%

8

-4.336(-4.886, -3.785)

0.000

93.30%

Animal species

 BALB/c

6

-0.330(-0.580, -0.081)

0.010

39.50%

6

-7.771(-8.545, -6.997)

0.000

0.00%

 SD

3

0.293(-0.191, 0.776)

0.236

0.00%

5

-2.906(-3.553, -2.258)

0.000

88.90%

Dosage

 H

3

-0.265(-0.655, 0.126)

0.185

59.00%

4

-4.486(-5.269, -3.703)

0.001

94.60%

 M

3

0.130(-0.297, 0.557)

0.550

0.00%

4

-4.314(-5.109, -3.519)

0.001

93.80%

 L

3

-0.366(-0.713, -0.019)

0.039

58.50%

3

-6.850(-7.939, -5.761)

0.000

69.70%

Quantity

 6

6

-0.330(-0.580, -0.081)

0.010

39.50%

8

-4.876(-5.460, -4.291)

0.000

94.50%

 8

3

0.293(-0.191, 0.776)

0.236

0.00%

3

-4.998(-5.939, -4.057)

0.000

0.00%

Gender

 F; M

6

-0.330(-0.580, -0.081)

0.010

39.50%

6

-7.771(-8.545, -6.997)

0.000

0.00%

 M

3

0.293(-0.191, 0.776)

0.236

0.00%

5

-2.906(-3.553, -2.258)

0.000

88.90%

  1. F females, M males, WMD weighted mean difference, BALB/c BALB/c mice, SD Sprague Dawley rats, H high M medium, L low