Table 2 Symptoms of anxiety, depression, fatigue, and insomnia among patients with and without self-reported chronic musculoskeletal pain (CMP). Observed data in each group is presented as number and percent or mean and standard deviation (SD), comparison between groups with mean difference, 95% Confidence Interval (CI) and p-value

Anxiety, mean ± SD

5.4 ± 3.9

3.7 ± 3.0

-1.8

-2.2, -1.3

˂0.01

 No anxiety

350 (72.0)

368 (88.7)

 Borderline anxiety

76 (15.6)

33 (8.0)

 Clinical anxiety

60 (12.3)

14 (3.4)

 Missing

31

37

Depression, mean ± SD

3.4 ± 3.3

2.0 ± 2.5

-1.4

-1.8, -1.1

˂0.01

 No depression

432 (88.7)

407 (95.3)

 Borderline depression

30 (6.2)

17 (4.0)

 Clinical depression

25 (5.1)

3 (0.7)

 Missing

30 (5.8)

25 (5.5)

Fatigue

 Total score, mean ± SD

14.2 ± 4.9

11.2 ± 4.2

-3.0

-3.6, -2.4

˂0.01

 Missing

48 (9.3)

40 (8.8)

 Physical fatigue sub-score, mean ± SD

9.7 ± 3.7

7.3 ± 3.1

-2.4

-2.8, -2.0

˂0.01

 Missing

31 (4.9)

26 (5.6)

 Mental fatigue sub-score, mean ± SD

4.6 ± 1.7

3.9 ± 1.5

-0.6

-0.9, -0.4

˂0.01

 Missing

33 (6.4)

27 (6.0)

Insomnia

 Total score, mean ± SD

8.1 ± 6.1

4.4 ± 4.3

-3.8

-4.5, -3.1

˂0.01

 No clinical insomnia

261 (54.8)

328 (78.3)

 Sub-threshold insomnia

137 (28.8)

82 (19.6)

 Moderate/severe clinical insomnia

78 (16.4)

9 (2.1)

 Missing

41 (7.9)

33 (7.3)