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Table 4 Results of the ROC Curve Analysis on serum SOD and CRP Between culture-negative PJI group and non-PJI group

From: Decreased serum superoxide dismutase concentration has a high value for the diagnosis of periprosthetic joint infection—a single-center, retrospective study

 

AUC

95%CI

Optimal cutoff

Youden index

Sensitivity

Specificity

PPV

NPV

P-Value

CRP

0.909

0.842—0.954

 > 13 mg/L

0.77

83.3

90

83

93

 < 0.0001

SOD

0.908

0.840—0.953

 ≤ 149U/ml

0.7

72.2

98

72

98

 < 0.0001

CRP + SOD

0.972

0.864–0.967

——

0.72

77.8

94

78

98

 < 0.0001

  1. CRP C-reactive protein, SOD superoxide dismutase, PPV Positive Predictive Value, NPV Negative Predictive Value, LR + positive likelihood ratio, LR − negative likelihood ratio