Fig. 2

Comparison between histological and μCT images

Representative histochemical staining of distal femur (HE, on left) and μCT images of whole femur (sagittal, coronal, and axial planes, respectively) in young mature adult WT and Nrf2-specific KO mice, next to old WT and KO mice. Trabecular bone was absent in old KO mice (asterisks). HE, hematoxylin and eosin; WT, wild-type; Nrf2, Nuclear factor erythroid 2–related factor 2; KO, knockout