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Table 6 Associations with radiographic knee osteoarthritis (RKOA), according to Ahlbäck grade I, in the subgroup with overweight/obesity (BMI ≥ 25, n = 156) according to body mass index (BMI). Two models were used, one univariate and one adjusting for age and sex

From: Associations between metabolic factors and radiographic knee osteoarthritis in early disease - a cross-sectional study of individuals with knee pain

 

Univariate logistic regression

Adjusting for age and sex

 

OR

95% CI

p-value

OR

95% CI

p-value

Age, years

1.14

1.06,1.22

< 0.001

1.14

1.06, 1.22

< 0.001

Sex, women

1.04

0.50,2.14

0.92

   

Visceral fat area (VFA), cm2

1.00

0.99,1.01

0.79

   

Raised VFA (≥ 100), cm2

0.99

0.40,2.45

0.99

   

Proportion of fat, %

1.00

0.96,1.05

0.84

   

Waist circumferance, cm

1.01

0.97,1.04

0.78

   

Central obesity*

--

     

Raised blood pressure*

1.16

0.57,2.36

0.68

   

CRP, mg/L

0.96

0.84,1.10

0.56

   

Total cholesterol, mmol/L

1.02

0.74,1.41

0.88

   

Triglycerides, mmol/L

1.26

0.78,2.06

0.34

   

Raised triglycerides*

1.81

0.78,4.25

0.17

1.55

0.62, 3.88

0.35**

LDL-Cholesterol, mmol/L

1.09

0.78,1.52

0.62

   

Reduced HDL-Cholesterol mmol/L*

1.00

0.41,2.47

0.99

   

Glucose, mmol/L

0.89

0.58,1.37

0.61

   

Raised glucose*

0.71

0.35,1.46

0.36

   

HbA1c, mmol/mol

0.97

0.89,1.05

0.42

   

MetS*

1.17

0.57,2.39

0.68

   
  1. BMI, body mass index; CRP, C-reactive protein; LDL, low density lipoprotein; HDL, high density lipoprotein; HbA1C, glycosylated hemoglobin; MetS, metabolic syndrome
  2. *according to International Diabetes Federation (IDF) **controlled for age