Associations between metabolic factors and radiographic knee osteoarthritis in early disease - a cross-sectional study of individuals with knee pain

Table 5 Description of the overweight/obese (BMI ≥ 25, n = 156) subgroup, with and without radiographic knee osteoarthritis (RKOA)

	Missing No OA/OA	No OA Mean (sd)	RKOA* Mean(sd)	p-value
N		113	43
Age, years	0/0	51 (8)	56 (4)	< 0.001
Sex, women, %	0/0	62	63	0.92
Visceral fat area (VFA), cm²	2/1	144 (48)	147 (49)	0.79
Raised VFA, %	2/1	81	81	0.99
Proportion of fat, %	2/1	35 (9)	35 (8)	0.84
Waist circumferance, cm	2/0	104 (10)	104 (10)	0.79
Central obesity, %	2/0	98	100	0.38
Raised blood pressure**, %	1/0	54	58	0.68
CRP, mg/L	0/0	2.7 (3.3)	2.4 (2.4)	0.56
Total cholesterol, mmol/L	0/0	5.4 (1.1)	5.5 (1.0)	0.89
Triglycerides, mmol/L	0/0	1.2 (0.7)	1.3 (0.7)	0.34
Raised triglycerides**, %	0/0	16	26	0.17
LDL, mmol/L	0/0	3.7 (1.1)	3.8 (1.0)	0.62
HDL, mmol/L	0/0	1.6 (0.4)	1.5 (0.4)	0.24
Reduced HDL**	0/0	19	19	0.99
Glucose, mmol/L	0/0	5.7 (1.1)	5.6 (0.6)	0.60
Raised glucose**, %	0/0	48	39	0.36
HBA1c, mmol/mol	6/1	38 (6)	37 (4)	0.42
MetS**, %	3/0	38	42	0.68

RKOA, radiographic knee osteoarthritis; BMI, body mass index; CRP, C-reactive protein; LDL, low density lipoprotein; HDL, high density lipoprotein; HbA1C, glycosylated hemoglobin; MetS, metabolic syndrome
*Ahlbäck grade I or more in at least one knee **according to International Diabetes Federation (IDF)

ISSN: 1471-2474