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Table 4 Associations with radiographic knee osteoarthritis(RKOA, Ahlbäck grade I or more in at least one knee) in the subgroup with normal BMI (n = 126) analysed with two logistic regression models. One univariate and one adjusting for age and sex

From: Associations between metabolic factors and radiographic knee osteoarthritis in early disease - a cross-sectional study of individuals with knee pain

 

Univariate logistic regression

Adjusting for age and sex

 

OR

95% CI

p-value

OR

95% CI

p-value

Age, years

1.12

1.04,1.22

0.006

1.13

1.04, 1.22

0.006

Sex, women

1.11

0.34,3.64

0.86

   

Visceral fat area (VFA), cm2

1.02

1.00,1.04

0.017

1.02

1.01,1.04

0.014

Raised VFA (≥ 100), cm2

7.04

2.28,21.69

0.001

9.58

2.55,35.94

0.001

Proportion of fat, %

1.06

0.99,1.15

0.11

1.09

0.98, 1.22

0.11

Waist circumferance, cm

1.04

0.99,1.10

0.13

1.06

0.99, 1.13

0.08

Central obesity*

3.50

1.10,11.17

0.034

2.93

0.89,9.69

0.08**

Raised blood pressure*

0.42

0.16,1.12

0.08

0.51

0.18,1.44

0.20

CRP, mg/L

1.39

1.06,1.82

0.017

1.33

0.98,1.82

0.07

Total cholesterol, mmol/L

1.79

1.12,2.86

0.016

1.58

0.95,2.63

0.08

Triglycerides, mmol/L

1.14

0.39,3.34

0.82

   

Raised triglycerides*

1.79

0.18,18.13

0.62

   

LDL-Cholesterol, mmol/L

1.61

0.98,2.64

0.06

1.45

0.85,2.47

0.18

Reduced HDL-Cholesterol mmol/L*

0.87

0.10,7.63

0.90

   

Glucose, mmol/L

0.83

0.30,2.60

0.72

   

Raised glucose*

0.98

0.30,3.23

0.97

   

HbA1c, mmol/mol

1.13

0.97,1.31

0.11

1.07

0.90, 1.26

0.44

MetS*

1.25

0.32,4.86

0.75

   
  1. CRP, C-reactive protein; LDL, low density lipoprotein; HDL, high density lipoprotein; HbA1C, glycosylated hemoglobin; MetS, metabolic syndrome
  2. *according to International Diabetes Federation (IDF) **controlled only for age ***. Cholesterol and LDL-cholesterol was also controlled for lipid-lowering treatment and HbA1c for treatment for diabetes