Fig. 3

Muscle weight outcomes. Characteristic muscle weight dynamics are presented as absolute wet weights and as a percentage change of the VML hindlimb relative to its matched contralateral for study endpoints ranging from 3–90 days post-injury for both the tibialis anterior (TA) muscle (A and B) and the synergistic extensor longus (EDL) muscle (C and D), respectively. E Simple linear regression analysis comparing absolute weights of TA and EDL muscles in VML (clear) and healthy contralateral (grey) limbs with best fit lines and 95% confidence intervals represented by black and red dashed lines, respectively. F Simple linear regression of TA and EDL muscle weights presented as a percentage changes of the VML affected hindlimb relative to its matched contralateral. All panels represent data pooled from all experiments studied with individual data points represented as open circles. Bar graphs represent the group mean ± standard error. * Indicates a difference between VML and contralateral TA muscles at the specified timepoint (P < 0.05)