Abnormal TNS3 gene methylation in patients with congenital scoliosis

Table 2 Differentially methylated regions

Position	Differential Methylation Region Start	Differential Methylation Region End	P Value	Nromal Methylation	CS Methylation	Gene ID	Symbol	Log2 Ratio(C/N)
chr7	47,622,153	47,622,200	0.011	0.5617	0.79	64,759	TNS3	0.492
chr7	80,549,131	80,549,364	0.00084	0.60842	0.36625	10,512	SEMA3C	-0.732
chr8	37,653,890	37,653,973	0.0068	0.7515	0.8664	25,960	GPR124	0.205
chr7	130,130,288	130,130,549	0.0029	0.66906	0.55711	4232	MEST	-0.487
chr14	101,192,682	101,192,751	0.00073	0.7755	0.8962	8788	DLK1	0.209
chr8	50,824,309	50,824,417	0.0004	0.069437	0.1755	54,212	SNTG1	1.338
chr15	64,456,244	64,456,426	0.013	0.51943	0.37429	5479	PPIB	-0.473
chr16	90,014,349	90,014,430	0.0089	0.1555	0.3232	54,849	DEF8	1.056
chr8	102,504,447	102,504,502	0.023	0.1583	0.0404	79,977	GRHL2	-1.97

ISSN: 1471-2474