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Table 3 Comparison of bone metabolism parameters of patients with OSA and control subjects

From: Assessment of bone mineral density and bone metabolism in young men with obstructive sleep apnea: a cross-sectional study

 

Controls

Moderate OSA

Severe OSA

p values

Subjects (n)

15

27

43

 

Calcium (mmol/L)

2.33 ± 0.16

2.27 ± 0.09

2.24 ± 0.10

0.506

Phosphorus (mmol/L)

1.18 ± 0.04

1.15 ± 0.13

1.11 ± 0.24

0.879

25-(OH) vitamin D (ng/ml)

20.37 ± 7.78

20.34 ± 6.93

19.66 ± 6.61

0.931

β-CTx (ng/ml)

0.59 ± 0.15

0.51 ± 0.16

0.46 ± 0.18

0.243

Osteocalcin (ng/ml)

21.34 ± 7.29

21.47 ± 4.67

19.23 ± 5.80

0.337

PINP (ng/ml)

47.39 ± 15.82

53.18 ± 16.49

42.74 ± 16.59

0.096

Lumbar L1–L4 BMD (g/cm2)

1.10 ± 0.14

1.28 ± 0.24

1.14 ± 0.17

0.036*

Femur neck BMD (g/cm2)

0.96 ± 0.11

1.02 ± 0.10

1.00 ± 0.12

0.463

Hip total BMD (g/cm2)

0.97 ± 0.11

1.02 ± 0.09

1.06 ± 0.12

0.360

Lumbar L1–L4 t score

0.37 ± 1.07

0.27 ± 0.97

-0.19 ± 1.41

0.379

Femur neck t score

-0.09 ± 1.04

-0.08 ± 0.61

-0.15 ± 1.04

0.968

Hip total t score

-0.17 ± 0.87

0.19 ± 0.69

0.58 ± 0.95

0.355

  1. OSA Obstructive sleep apnea, β-CTx β-isomerized form C-terminal telopeptideof type I collagen, PINP Procollagen type I N-propeptide, BMD Bone mineral density,  *p was considered statistically significant