Utilization of T1-Mapping for the pelvic and thigh muscles in Duchenne Muscular Dystrophy: a quantitative biomarker for disease involvement and correlation with clinical assessments

Peng, Fei; Xu, Huayan; Song, Yu; Xu, Ke; Li, Shuhao; Cai, Xiaotang; Guo, Yingkun; Gong, Lianggeng

doi:10.1186/s12891-022-05640-y

Table 3 Spearman correlation between individual muscle T1-value and clinical assessments

From: Utilization of T1-Mapping for the pelvic and thigh muscles in Duchenne Muscular Dystrophy: a quantitative biomarker for disease involvement and correlation with clinical assessments

T1-value of individual muscle
	GMa	GMe	GMi	IP	TF	OI	Pe	RF	VL	VI	VM	Gr	Sa	AL	AB	AM	St	Sm	BFLH
Age (n = 92)	−.334^**	−.623^**	−.445^**	−.347^**	−.515^**	−.461^**	−.587^**	−.507^**	−.577^**	−.629^**	−.566^**	−.297^**	−.379^**	−.457^**	−.482^**	−.418^**	−.505^**	−.535^**	−.616^**
Height (n = 92)	−.404^**	−.529^**	−.354^**	−.314^**	−.521^**	−.333^**	−.531^**	−.430^**	−.559^**	−.571^**	−.519^**	−.244^*	−.359^**	−.355^**	−.442^**	−.365^**	−.439^**	−.452^**	−.546^**
Weight (n = 92)	−.373^**	−.470^**	−.376^**	−.196	−.419^**	−.314^**	−.455^**	−.405^**	−.495^**	−.449^**	−.393^**	−.197	−.357^**	−.337^**	−.294^**	−.283^**	−.380^**	−.415^**	−.479^**
BMI (n = 92)	−.225	−.241	−.255^*	−.063	−.210	−.166	−.257^*	−.279^*	−.261^*	−.179	−.156	−.082	−.218	−.173	−.095	−.132	−.212	−.286^*	−.257^*
NSAA (n = 92)	.527^**	.689^**	.529^**	.419^**	.705^**	.431^**	.631^**	.607^**	.709^**	.707^**	.676^**	.232^*	.330^*	.484^**	.615^**	.565^**	.484^**	.597^**	.721^**
10-m run/walk (n = 77)	−.506^**	−.566^**	−.182	−.050	−.524^**	−.057	−.360^**	−.343^**	−.593^**	−.526^**	−.469^**	. 074	.067	−.110	−.366^**	−.605^**	−.125	−.268^*	−.578^**
Gowers (n = 68)	−.586^**	−.545^**	−.147	.087	−.475^**	.052	−.366^**	−.257	−.601^**	−.480^**	−.388^**	. 066	.086	.042	−.215	−.705^**	.034	−.172	−.509^**
4-stair climb (n = 68)	−.496^**	−.592^**	−.188	.056	−.415^**	−.026	−.235	−.323^*	−.599^**	−.467^**	−.308^*	.146	.117	−.145	−.229	−.668^**	−.047	−.192	−.540^**
4-stair descend (n = 68)	−.480^**	−.448^**	−.241	−.004	−.333^**	−.020	−.203	−.240	−.527^**	−.457^**	−.337^**	.220	.100	−.120	−.204	−.472^**	−.032	−.088	−.382^**
CK (n = 92)	.354^**	.373^**	.292^**	.167	.422^**	.208	.418^**	.491^**	.439^**	.479^**	.432^**	.054	.160	.191	.363^**	.308^**	.320^**	.396^**	.467^**

All statistics were evaluated based on Spearman correlation corrected by the Benjamini-Hochberg procedures. * P < 0.05, ** P < 0.01. GMa Gluteus maximus, GMe Gluteus medius, GMi Gluteus minimus, IP Iliopsoas, TF Tensor fascia, OI Obturator internus, Pe Pectineus, RF Rectus femoris, VL Vastus lateralis, VI Vastus intermedius, VM Vastus medialis, Gr Gracilis, Sa Sartorius, AL Adductor longus, AB Adductor brevis, AM Adductor magnus, St Semitendinosus, Sm Semimembranosus, BFLH Biceps femoris long head, BMI Body mass index, NSAA Northstar ambulatory assessment, CK Creatine kinase

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ISSN: 1471-2474

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