Association between total bilirubin and bone mineral density level in adolescents

Table 4 Multivariable adjusted associations among quartile of bilirubin and bone mass density by sex

	Total femur BMD	Femur neck BMD	Trochanter BMD	Intertrochanter BMD	Lumbar spine BMD
	β (95% CI) P value	β (95% CI) P value	β (95% CI) P value	β (95% CI) P value	β (95% CI) P value
Male
Bilirubin (Quintile)
Q1	Ref	Ref	Ref	Ref	Ref
Q2	0.017 (-0.008, 0.043) 0.182	0.024 (-0.001, 0.048) 0.058	0.011 (-0.012, 0.034) 0.348	0.019 (-0.009, 0.048) 0.188	0.019 (-0.003, 0.042) 0.096
Q3	0.029 (0.004, 0.055) 0.024	0.028 (0.003, 0.052) 0.027	0.027 (0.004, 0.050) 0.023	0.030 (0.001, 0.059) 0.043	0.024 (0.001, 0.046) 0.039
Q4	0.038 (0.013, 0.063) 0.003	0.036 (0.012, 0.060) 0.004	0.034 (0.011, 0.057) 0.003	0.040 (0.012, 0.069) 0.006	0.035 (0.013, 0.058) 0.002
P for trend	< 0.001	0.005	< 0.001	0.001	< 0.001
Female
Bilirubin (Quintile)
Q1	Ref	Ref	Ref	Ref	Ref
Q2	0.003 (-0.011, 0.017) 0.690	0.004 (-0.010, 0.018) 0.586	-0.000 (-0.014, 0.013) 0.946	0.007 (-0.010, 0.023) 0.424	-0.002 (-0.016, 0.012) 0.814
Q3	0.008 (-0.008, 0.023) 0.348	0.009 (-0.007, 0.025) 0.278	0.004 (-0.010, 0.019) 0.548	0.010 (-0.008, 0.028) 0.29	0.003 (-0.012, 0.019) 0.683
Q4	0.021 (0.003, 0.038) 0.020	0.018 (0.000, 0.035) 0.048	0.022 (0.006, 0.038) 0.007	0.022 (0.002, 0.042) 0.032	0.015 (-0.002, 0.032) 0.091
P for trend	0.016	0.036	0.005	0.033	0.063
P for interaction	0.116	0.177	0.123	0.146	0.059

Adjust for: age (continuous), race (non-Hispanic white, black, Mexican American, other Hispanic, other race/ethnicity or missing), education (less than high school, high school, more than high school, or missing), income (less than $ 25,000, $ 25,000–74,999, more than $ 75,000, or missing), body mass index (underweight, normal weight, overweight, obese, or missing), calcium intake, and diabetes (continuous)

ISSN: 1471-2474