Table 1 Genes and gene categories. Panel of 42 functional genes associated with adipogenic/metabolic, atrophic, fibrogenic, inflammatory, and myogenic pathways in skeletal muscle. Genes were examined using qPCR on custom cDNA plates containing these 42 genes of interest, and 40S Ribosomal Protein (RPS18) and Beta-Actin (ACTB) as controls

Gene Name (Abbreviation)

Peroxisome Proliferator-Activated Receptor Gamma (PPARG), PPARG Coactivator 1 Alpha (PPARGC1A), Peroxisome Proliferator-Activated Receptor Delta (PPARD),

Fatty Acid Binding Protein 4 (adipocyte specific) (FABP4), CCATT/Enhancer Binding Protein Alpha (CEBPA), Adiponectin (ADIPOQ),

Wnt Family Member 10B (WNT10B)

Protein Tyrosine Phosphatase Non-receptor Type 4 (PTPN4)

Myostatin/ Growth Differentiation Factor 8 (MSTN),

Activin Receptor 2B (ACVR2B), Tripartite Motif Containing 63/E3 Ubiquitin Ligase (TRIM63), Forkhead Box O3 (FOXO3),

F-box only protein 32 (FBXO32) Caspase-3 (CASP3), Caspase-1 (CASP1)

Platelet-Derived Growth Factor Receptor Alpha (PDGFRA),

Tissue Inhibitor of Metalloproteinase 3 (TIMP3),

Tissue Inhibitor of Metalloproteinase 1 (TIMP1),

Matrix Metalloproteinase 9 (MMP9),

Matrix Metalloproteinase 3 (MMP3),

Matrix Metalloproteinase 1 (MMP1),

Lysyl Oxidase (LOX),

Fibronectin 1 (FN1),

Connective Tissue Growth Factor (CTGF),

Collagen Type III Alpha 1 Chain (COL3A1),

Collagen type I Alpha Chain (COL1A1),

Transforming Growth Factor Beta 1 (TGFB1)

Tumor Necrosis Factor (TNF),

Interleukin-6 (IL6),

Interleukin-10 (IL10),

Interleukin-1 Beta (IL1B)