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Table 5 Comparison of clinical and quantitative MRI data between active and inactive AS groups

From: T2 mapping and fat quantification of lumbar paraspinal muscle in ankylosing spondylitis: a case control study

Variables, N (%) or mean ± SD

Active AS group (n = 8)

Inactive AS group (n = 29)

P value

Clinical data

 Age, y

26.38 ± 3.82

28.00 ± 8.05

0.899a

 Sex/M

6 (75%)

21 (72.4%)

1.000b

 BMI, kg/m2

20.41 ± 3.78

20.94 ± 3.11

0.731c

 Disease duration, y

3.37 ± 2.51

7.03 ± 4.71

0.021a

 ESR, mm/H

45.75 ± 46.79

16.65 ± 17.12

0.008a

 CRP, mg/L

42.24 ± 46.08

14.50 ± 20.07

0.016a

 BASFI Score (0–10)

0.91 ± 1.27

0.22 ± 0.35

0.118a

 BASDAI Score (0–10)

5.91 ± 1.59

1.52 ± 1.06

0.000a

Quantitative MRI assessments

 L3/4 MF CSA, mm2

534.38 ± 69.42

524.81 ± 82.21

0.766a

 L3/4 ES CSA, mm2

1619.63 ± 396.71

1563.36 ± 270.45

0.642a

 L4/5 MF CSA, mm2

863.75 ± 122.51

816.87 ± 160.76

0.451a

 L4/5 ES CSA, mm2

1288.00 ± 240.29

1272.98 ± 241.47

0.877a

 L3/4 MF FF, %

27.32 ± 8.63

28.16 ± 9.29

0.871c

 L3/4 ES FF, %

30.38 ± 9.26

31.38 ± 7.13

0.814c

 L4/5 MF FF, %

32.07 ± 9.05

30.43 ± 7.51

0.299c

 L4/5 ES FF, %

35.70 ± 9.97

35.99 ± 7.16

0.651c

 L3/4 MF T2non-fatsat value, ms

54.69 ± 9.64

50.46 ± 6.64

0.124c

 L3/4 ES T2non-fatsat value, ms

50.98 ± 6.84

47.94 ± 5.94

0.226c

 L4/5 MF T2non-fatsat value, ms

55.91 ± 8.96

51.56 ± 6.52

0.132c

 L4/5 ES T2non-fatsat value, ms

56.52 ± 7.86

51.68 ± 7.20

0.108c

 L3/4 MF T2fatsat value, ms

42.74 ± 4.75

39.69 ± 2.72

0.024a

 L3/4 ES T2fatsat value, ms

40.09 ± 2.62

38.07 ± 2.03

0.026a

 L4/5 MF T2fatsat value, ms

40.11 ± 4.89

39.04 ± 4.48

0.559a

 L4/5 ES T2fatsat value, ms

40.73 ± 2.68

39.17 ± 2.41

0.123a

  1. Note: The values are given as frequencies (percentages) or means ± standard deviation; a Mann–Whitney U test; b Pearson chi-squared test; c independent samples t test; A p-value of < 0.05 was considered to indicate statistical significance
  2. Y years, M male, AS Ankylosing spondylitis, ESR Erythrocyte sedimentation rate, CRP C-reactive protein, BMI body mass index, BASFI Bath AS function index, BASDAI Bath AS disease activity index, FF Fat fraction, MF Multifidus, ES Erector spinae, CSA Cross-sectional area