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Table 2 Intergroup comparison of TDO2, IL-1β, and TNF-α levels in synovium (mean ± SEM)

From: High levels of TDO2 in relation to pro-inflammatory cytokines in synovium and synovial fluid of patients with osteoarthritis

Variables

Control group (n = 20)

OA group (n = 41)

Statistics (F)

P

TDO2 in synovium (ng/g)

39.20 ± 1.90

52.02 ± 1.97

4.487

0.039

IL-1β in synovium (pg/g)

419.16 ± 20.95

586.44 ± 23.15

9.17

0.004

TNF-α in synovium (pg/g)

449.17 ± 28.64

701.02 ± 18.62

21.59

 < 0.001

  1. IL-1β interleukin-1β, SEM Standard error of mean, TDO2 Tryptophan 2,3-dioxygenase, TNF-α Tumor necrosis factor-α, OA Osteoarthritis
  2. Sex and BMI were used as covariates