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Table 7 Inflammatory and structural genes in the multifidus between mild—and severe-degeneration groups (Data is presented as Mean ± SD)

From: Correlation between the fatty infiltration of paraspinal muscles and disc degeneration and the underlying mechanism

 

mild-degeneration

severe-degeneration

P-value

Inflammatory markers

 TNF

1.097(0.563)

1.447(0.339)

0.304

 IL1-β

0.621(0.362)

0.827(0.589)

0.609

 IL-6

0.468(0.477)

0.818(0.383)

0.293

 IL-8

0.407(0.515)

0.462(0.289)

0.850

 NOS2

0.815(0.182)

0.972(0.536)

0.649

 TGF-β

1.006(0.312)

1.064(0.412)

0.841

  1. Data are expressed as 2−ΔΔC.t. Mean (standard deviation) is shown TNF Tumor necrosis factor, IL-1β Interleukin-1β, IL-6 Interleukin-6, IL-8 Interleukin-8, NOS2 Nitric oxide synthase 2, TGF-β Transforming growth factor-β, GAPDH Glyceraldehyde 3-phosphate dehydrogenase
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BMC Musculoskeletal Disorders

ISSN: 1471-2474

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