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Table 6 Inflammatory and structural genes in the lumbar disc between mild—and severe-degeneration groups (Data is presented as Mean ± SD)

From: Correlation between the fatty infiltration of paraspinal muscles and disc degeneration and the underlying mechanism

 

Mild-degeneration

Severe-degeneration

P-value

Inflammatory markers

 TNF

1.307(1.204)

8.96(3.216)

0.018

 IL1-β

0.421(0.501)

0.405(0.217)

0.951

 IL-6

0.828(0.471)

0.996(0.734)

0.738

 IL-8

0.440(0.501)

0.266(0.180)

0.490

 NOS2

3.388 (3.425)

13.950 (8.111)

0.081

 TGF-β

2.76 (1.672)

6.943 (2.859)

0.064

  1. Data are expressed as 2−ΔΔC.t. Mean (standard deviation) is shown TNF Tumor necrosis factor, IL-1β Interleukin-1β, IL-6 Interleukin-6, IL-8 Interleukin-8, NOS2 Nitric oxide synthase 2, TGF-β Transforming growth factor-β, GAPDH Glyceraldehyde 3-phosphate dehydrogenase
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BMC Musculoskeletal Disorders

ISSN: 1471-2474

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