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Fig. 2 | BMC Musculoskeletal Disorders

Fig. 2

From: Intra-articular injection of monoiodoacetate induces diverse hip osteoarthritis in rats, depending on its dose

Fig. 2

Radiography and histopathology of the hip. Radiography and histopathology of the hip in the Sham and MIA groups (0.25-mg, 0.5-mg, 1.0-mg, 2.0-mg, and 4.0-mg) 12 weeks after MIA administration. af Anteroposterior radiographs of the rat hip. gl Hematoxylin and eosin-stained tissues. mr Safranin O-stained tissues. As the MIA dose increased, OA changes progressed both radiologically and histologically. At concentrations of 0.5 mg MIA and higher, end-stage joint destruction was observed at 12 weeks. Abbreviations: MIA, monoiodoacetate; OA, osteoarthritis

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