Table 3 List of human plasma proteins identified by LDSC ^c for eBMD^d (P value < 0.05)

Receptor-interacting serine/threonine-protein kinase 2

RIPK2

−0.2357

0.0072

C-X-C motif chemokine 16

CXCL16, soluble

0.2008

0.0119

C-C motif chemokine 5

RANTES

−0.2108

0.0145

Cathepsin Z

CATZ

0.1998

0.0178

Interleukin-7

IL-7

−0.2414

0.0212

Cysteine-rich hydrophobic domain-containing protein 2

CHIC2

0.1121

0.0256

Phenylalanine--tRNA ligase, mitochondrial

SYFM

0.2221

0.0256

Corticotropin-releasing factor-binding protein

CRHBP

0.1533

0.0297

O-acetyl-ADP-ribose deacetylase MACROD1

MACD1

0.1633

0.0319

Guanylate cyclase activator 2B

GUC2B

0.2065

0.033

SPARC-like protein 1

SPARCL1

0.1513

0.0362

Dickkopf-related protein 4

Dkk-4

−0.2058

0.0373

E3 ubiquitin-protein ligase ZNRF3

ZNRF3

0.1993

0.0419

Cellular retinoic acid-binding protein 1

RABP1

0.1496

0.0428

Cell growth regulator with EF hand domain protein 1

CGRE1

−0.1792

0.0436

Serine/threonine-protein kinase pim-1

PIM1

0.2707

0.0446

Creatine kinase M-type

CK-MM

0.2035

0.0471

Alpha-2-antiplasmin

a2-Antiplasmin

0.2072

0.0478

Tenascin-X

Tenascin-X

0.3227

0.0483

Thrombospondin-3

TSP3

0.2816

0.0488

Dickkopf-related protein 1

DKK1

−0.177

0.0495