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Table 2 Comparison of serum BTMs levels in each group

From: Association of bone-related biomarkers with femoral neck bone strength

Parameters Normal a (n = 27) Osteopenia b (n = 27) Osteoporosis c (n = 27) Severe osteoporosis d (n = 27) P-value
CTX
(ng/ml)
0.29 ± 0.14 0.52 ± 0.16* 0.65 ± 0.20* 0.78 ± 0.23*#  < 0.0001
PINP (ng/ml) 44.00 ± 12.55 48.30 ± 15.95 62.11 ± 21.04* 65.04 ± 23.73*  < 0.0001
OC
(ng/ml)
8.33 ± 4.18 10.41 ± 4.67 17.70 ± 8.26*# 18.75 ± 10.45*#  < 0.0001
  1. Data are presented as the mean ± SD for CTX, PINP and OC
  2. a T-score ≥ -1.0
  3. b T-score < -1.0 and > -2.5
  4. c At least one of the following criteria fulfilled: (a) T-score ≤ -2.5; (b) femoral neck fragile fracture)
  5. d Fragility fracture with a T-score ≤ -2.5
  6. *P < 0.05, compared with normal group
  7. #P < 0.05, compared with osteopenia group
  8. P < 0.05, compared with OP group
  9. CTX C-terminal telopeptide of type I collagen, PINP type I procollagen N-terminal propeptide, OC osteocalcin