From: Influence of frailty and its interaction with comorbidity on outcomes among total joint replacement
Parameter | Non-Frail | Frail | P Value |
---|---|---|---|
Total(n = count) | 1,979,458 | 50,385 | - |
Total incidence | Â | 2.5% | Â |
Age (mean ± standard deviation, yrs.) | 67.14 ± 0.03 | 74.31 ± 0.28 |  < 0.0001 |
Age group (years) |  |  |  < 0.0001 |
  ≤ 40 | 1.4% | 0.82% |  |
 40–64 | 39.3% | 20.3% | |
 65–80 | 45.7% | 42.6% | |
  ≥ 80 | 13.6% | 36.28% | |
Sex |  |  |  < 0.0001 |
 Male | 38.5% | 33.6% |  |
 Female | 61.5% | 66.4% |  |
Race |  |  |  < 0.0001 |
 White | 71% | 74.6% |  |
 Black | 5.8% | 5.7% | |
Hispanic | 3.9% | 3.9% | |
Asian or Pacific Islander | 1% | 1.1% | |
Native American | 0.4% | 0.36% | |
Other | 1.8% | 1.6% | |
Nature of admission |  |  |  < 0.0001 |
 Emergency/Urgent | 14.7% | 45% |  |
 Elective | 85.1% | 54.8% |  |
Comorbidity |  |  |  < 0.0001 |
 0 | 0.93% | 4.5% |  |
 1 | 4.4% | 1.7% |  |
 2 | 14.8% | 5.4% |  |
  ≥ 3 | 79.8% | 92.5% |  |
Medical complications | |||
 Acute cardiac event | 4.1% | 12.8% |  < 0.0001 |
 Acute pulmonary edema/failure | 0.57% | 4.3% |  < 0.0001 |
 Acute cerebrovascular event | 0.1% | 0.3% |  < 0.0001 |
 Acute renal failure | 2.2% | 9.0% |  < 0.0001 |
 Acute hepatic failure | 0.03% | 0.3% |  < 0.0001 |
 Pneumonia | 0.9% | 5.4% |  < 0.0001 |
 Urinary tract infection | 0.4% | 0.6% |  < 0.0001 |
Surgical complications | Â | Â | Â |
 Postoperative infection | 0.1% | 0.2% |  < 0.0001 |
 Accidental perforation or laceration of blood vessel, nerve, or organ | 0.1% | 0.1% |  < 0.0001 |
 mechanical complication of prosthetic joint | 0.6% | 1.9% |  < 0.0001 |
 DVT/PEa | 0.7% | 1.7% |  < 0.0001 |
Average cost of hospitalization | 49,402$(47,731,47,831) | 69,113$ |  < 0.0001 |
Death rate | 0.3% | 2.4% |  < 0.0001 |