Joint | Joint-specific questionnaires | LSM change from baseline (95% CI) | ||
---|---|---|---|---|
DF-HA | Placebo | Difference | ||
Hip | N | 46 | 44 | |
(WOMACa) | Pain subscore (mm) | −26.5 (−35.1 to −18.0) | −17.3 (−26.8 to −7.8) | −9.2 (−17.1 to − 1.4) |
Stiffness subscore (mm) | −27.7 (−36.3 to −19.1) | −20.0 (− 29.6 to − 10.4) | −7.8 (− 15.5 to 0.0) | |
Physical function subscore (mm) | −27.3 (−35.7 to −18.8) | −17.4 (−26.8 to −8.0) | −9.9 (−17.5 to −2.3) | |
Total score (mm) | −27.1 (−35.3 to −18.8) | −17.4 (−26.5 to −8.2) | −9.7 (−17.2 to −2.2) | |
Ankle | N | 30 | 30 | |
(SAFE-Qb) | Pain and pain-related | 21.3 (15.7 to 26.8) | 21.3 (15.3 to 27.3) | −0.1 (−6.6 to 6.5) |
Physical functioning and daily living | 16.7 (11.0 to 22.5) | 13.1 (6.8 to 19.3) | 3.7 (−3.1 to 10.5) | |
Social functioning | 9.9 (2.5 to 17.4) | 7.7 (−0.4 to 15.8) | 2.2 (−6.8 to 11.3) | |
Shoe-related | 10.6 (3.6 to 17.6) | 4.4 (−2.8 to 11.6) | 6.2 (−2.3 to 14.7) | |
General health and well-being | 14.9 (6.5 to 23.3) | 14.7 (5.4 to 24.0) | 0.2 (−9.9 to 10.3) | |
Sports activityc | 4.1 (−19.5 to 27.6) | −10.7 (−67.7 to 46.4) | 14.7 (−38.5 to 67.9) | |
Shoulder | N | 45 | 45 | |
(Shoulder36b) | Pain | 0.38 (0.23 to 0.53) | 0.41 (0.25 to 0.57) | −0.03 (−0.23 to 0.16) |
Range of motion | 0.44 (0.28 to 0.60) | 0.44 (0.27 to 0.60) | 0.00 (−0.20 to 0.20) | |
Muscle strength | 0.60 (0.41 to 0.80) | 0.53 (0.33 to 0.72) | 0.08 (−0.17 to 0.32) | |
General health | 0.28 (0.13 to 0.42) | 0.36 (0.21 to 0.51) | −0.09 (− 0.27 to 0.10) | |
Activities of daily living | 0.45 (0.29 to 0.61) | 0.39 (0.23 to 0.56) | 0.05 (− 0.15 to 0.26) | |
Ability to play sports | 0.42 (0.20 to 0.63) | 0.49 (0.27 to 0.71) | −0.07 (− 0.35 to 0.21) | |
Elbow | N | 25 | 25 | |
(PREE-Ja) | Pain score | −12.7 (−17.5 to −7.9) | − 15.4 (−20.2 to − 10.6) | 2.7 (−2.4 to 7.8) |
Function score | −5.2 (− 10.0 to − 0.3) | −9.7 (−14.4 to − 5.0) | 4.5 (−0.2 to 9.3) | |
Specific activities | − 9.7 (− 20.5 to 1.1) | −21.2 (−31.7 to −10.8) | 11.5 (1.1 to 22.0) | |
Usual activities | −5.0 (−9.2 to −0.9) | −7.3 (−11.3 to −3.3) | 2.3 (−1.8 to 6.4) | |
Total score | −17.0 (−26.5 to −7.4) | −25.1 (−34.4 to −15.9) | 8.2 (−1.4 to 17.8) |