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Table 5 Beta coefficients (B) and 95% confidence intervals (CIs) for the association between LDD score and bothersomeness of pain among individuals who reported any LBP (n = 802)

From: Association of lumbar disc degeneration with low back pain in middle age in the Northern Finland Birth Cohort 1966

Stratification

Unadjusted B (95% CI)

Adjusted1 B (95% CI)

1. All individuals with LBP (n = 802)

0.16 (0.09–0.24), P < 0.001

0.14 (0.05–0.22), P = 0.001

2. Mental distress (HSCL-25)

 No (n = 631)

0.19 (0.10–0.27), P < 0.001

0.16 (0.07–0.26), P < 0.001

 Yes (n = 171)

0.09 (−0.09–0.26), P = 0.343

0.05 (−0.15–0.25), P = 0.619

3. Number of pain sites

  < 2 (n = 401)

0.14 (0.03–0.24), P = 0.009

0.11 (0.00–0.23), P = 0.050

  ≥ 2 (n = 401)

0.19 (0.08–0.29), P < 0.001

0.16 (0.03–0.28), P = 0.014

4. Mental distress (HSCL-25) and pain sites combined

 No mental distress and < 2 pain sites (n = 333)

0.17 (0.06–0.28), P = 0.002

0.14 (0.02–0.26), P = 0.026

 No mental distress and ≥ 2 pain sites (n = 298)

0.20 (0.09–0.32), P < 0.001

0.18 (0.03–0.32), P = 0.016

 Mental distress and < 2 pain sites (n = 68)

−0.06 (−0.34–0.23), P = 0.691

−0.03 (−0.38–0.31), P = 0.841

 Mental distress and ≥ 2 pain sites (n = 103)

0.15 (−0.08–0.38), P = 0.188

0.08 (−0.18–0.34), P = 0.540

  1. 1adjusted for sex, smoking, BMI, education, leisure-time physical activity, occupational physical exposure, Modic changes, and herniations. LDD Lumbar disc degeneration, LBP Low back pain, HSCL-25 Hopkins Symptom Checklist-25