Table 5 Results and comparison of BTMs and inflammatory markers between the two groups

TRAP

1 week

3.70 ± 0.53

3.37 ± 0.24

0.702

4 weeks

2.99 ± 0.42

3.45 ± 0.67

0.491

8 weeks

2.86 ± 1.56

3.62 ± 1.48

0.266

12 weeks

1.87 ± 0.32

2.83 ± 1.02

0.158

16 weeks

6.52 ± 0.49

6.89 ± 0.97

0.581

P

<0.001

0.001

CTX-I

1 week

0.53 ± 0.14

0.72 ± 0.26

0.351

4 weeks

0.56 ± 0.14

0.50 ± 0.17

0.744

8 weeks

0.39 ± 0.25

0.58 ± 0.36

0.243

12 weeks

0.39 ± 0.08

0.45 ± 0.20

0.721

16 weeks

0.95 ± 0.26

0.76 ± 0.23

0.237

P

0.011

0.441

BGP

1 week

12.99 ± 1.71

12.97 ± 2.24

0.996

4 weeks

11.01 ± 0.50

10.36 ± 2.04

0.786

8 weeks

6.20 ± 3.16

10.03 ± 3.93

0.119

12 weeks

7.50 ± 1.56

10.76 ± 6.96

0.181

16 weeks

12.19 ± 2.94

11.39 ± 2.89

0.738

P

0.007

0.939

PINP

1 week

11.90 ± 1.15

13.57 ± 5.12

0.554

4 weeks

9.64 ± 1.30

8.22 ± 2.57

0.518

8 weeks

6.11 ± 3.66

8.84 ± 5.02

0.218

12 weeks

6.96 ± 1.84

8.89 ± 3.40

0.379

16 weeks

14.88 ± 2.01

13.35 ± 2.92

0.488

P

0.001

0.222

IL-6

1 week

12.79 ± 1.08

13.66 ± 4.30

0.881

4 weeks

11.93 ± 1.76

12.76 ± 1.27

0.853

8 weeks

11.65 ± 1.30

10.86 ± 2.90

0.863

12 weeks

13.21 ± 2.37

13.35 ± 3.57

0.977

16 weeks

23.17 ± 17.06

14.35 ± 5.39

0.059

P

0.284

0.734

TNF-α

1 week

24.61 ± 3.57

28.02 ± 7.60

0.725

4 weeks

25.72 ± 3.65

24.76 ± 2.83

0.898

8 weeks

24.17 ± 2.47

22.61 ± 5.92

0.835

12 weeks

25.42 ± 2.54

24.67 ± 5.63

0.920

16 weeks

45.59 ± 28.06

28.41 ± 8.60

0.011

P

0.172

0.704