Fig. 3From: Hyaluronic acid as an adjunct to microfracture in the treatment of osteochondral lesions of the talus: a systematic review of randomized controlled trialsMeta-analysis of the effect of microfracture of talar OCD lesions on VAS-pain scores, with versus without the addition of HA. Lower VAS-pain scores represent less pain. There is a very large effect in favor of utilizing HA (SMD − 3.86, 95% confidence interval − 4.75, − 2.97; P < .001) with moderate heterogeneity between studies (I-squared = 69%)Back to article page