Quality of life assessment after total knee arthroplasty in patients with Parkinson’s disease

Table 2 Unadjusted QOL outcomes

Measurement index	PD group (N = 12)	P¹	Matched group (N = 48)	P¹	P²
EQ- mobility
Pre-operative	1.89 ± 0.30		1.94 ± 0.34		0.79
Post-operative	1.89 ± 0.29	1.00	1.78 ± 0.39	0.03	0.29
EQ- self-care
Pre-operative	1.72 ± 0.47		1.49 ± 0.58		0.18
Post-operative	1.72 ± 0.55	1.00	1.35 ± 0.49	0.03	0.05
EQ-usual activities
Pre-operative	2.09 ± 0.54		2.09 ± 0.47		1.00
Post-operative	2.27 ± 0.65	0.63	1.79 ± 0.56	< 0.01*	0.02*
EQ- pain and discomfort
Pre-operative	2.19 ± 0.60		2.40 ± 0.57		0.31
Post-operative	2.37 ± 0.49	0.62	1.92 ± 0.58	< 0.01*	0.03
EQ- anxiety/depression
Pre-operative	1.72 ± 0.64		1.58 ± 0.55		0.55
Post-operative	1.46 ± 0.51	0.26	1.31 ± 0.55	< 0.01*	0.33
EQ-5D index
Pre-operative	0.559 ± 0.220		0.545 ± 0.218		0.81
Post-operative	0.531 ± 0.202	0.48	0.717 ± 0.208	< 0.01*	0.01*
PDQ- function
Pre-operative	57.8 ± 26.3		46.7 ± 21.6		0.18
Post-operative	53.3 ± 21.0	0.04	32.8 ± 24.3	< 0.01*	0.02*
PDQ- psychosocial
Pre-operative	32.1 ± 18.3		26.0 ± 14.5		0.41
Post-operative	27.3 ± 13.2	0.02*	18.2 ± 16.0	< 0.01*	0.09
PDQ-total
Pre-operative	91.0 ± 39.4		81.1 ± 33.1		0.18
Post-operative	81.4 ± 34.1	0.03	52.3 ± 35.4	< 0.01*	0.01*
PHQ-9
Pre-operative	9.48 ± 6.41		8.22 ± 7.02		0.49
Post-operative	8.22 ± 5.16	0.31	5.91 ± 6.45	< 0.01*	0.30
MCID
EQ-5D	3.25%		27.56%		0.04
PDQ	2.17%		23.48%		0.01*
PHQ-9	1.8%		13.27%		0.01*

*Statistically significant: P<0.02
¹Paired t test and Wilcoxon signed rank test are used for intra-group comparisons of parametric and nonparametric continuous variables, respectively
²The t-test and Fisher’s exact test were used for inter-group comparisons of continuous and categorical variables, respectively

ISSN: 1471-2474