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Table 6 RoC Curve Analysis for the diagnosis of patients with EOA or LOA

From: Associations between serum biomarkers of cartilage metabolism and serum hyaluronic acid, with risk factors, pain categories, and disease severity in knee osteoarthritis: a pilot study

Parameter

EOA

LOA

COMP

HA

PIICP

COMP

HA

PIICP

Sensitivity

47.7

50.0

52.7

49.2

47.5

96.2

Specificity

68.4

65.8

73.7

78.9

76.3

92.1

Youden Index

0.162

0.158

0.2596

0.282

0.240

0.8826

AUC

0.558

0.555

0.596

0.609

0.578

0.980

p-value

> 0.05

> 0.05

> 0.05

< 0.05

> 0.05

< 0.0001

95% CI

0.444–0.668

0.441–0.665

0.482–0.703

0.531–0.684

0.500–0.654

0.945–0.995

  1. EOA Early Osteoarthritis, LOA Late Osteoarthritis, AUC Area Under Curve, CI Confidence interval