| ILD |  | UIP |  | NSIP |  | AD | Emphysema |  | CLD(+) |  | CLD(−) | |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
 | P |  | P |  | P |  | P |  | P |  | P |  | |
Number, n | 115 | Â | 46 | Â | 69 | Â | 112 | Â | 37 | Â | 264 | Â | 189 |
Mean age, years (SD) | 67.2 (8.3) | 0.0009 | 67.1 (9.1) | 0.0137 | 67.3 (7.8) | 0.0061 | 65.6 (9.8) | 0.0553 | 66.3 (8.1) | 0.1247 | 66.4 (9.0) | 0.0013 | 62.8 (11.1) |
Male, n (%) | 27 (23.5) | *0.3076 | 16 (34.8) | *0.0267 | 11 (15.9) | *0.7155 | 15 (13.4) | *0.2667 | 22 (59.5) | *1.06 × 10−6 | 64 (24.2) | *0.1668 | 35 (18.5) |
Age at onset, years (SD) | 54.1 (12.9) | 0.0018 | 54.0 (14.3) | 0.0336 | 54.2 (12.0) | 0.0067 | 50.5 (14.6) | 0.2257 | 56.5 (11.2) | 0.0012 | 52.9 (13.6) | 0.0014 | 49.2 (13.2) |
Steinbrocker stages III and IV, n (%) | 53 (46.1) | *0.0773 | 25 (54.3) | *0.8687 | 28 (40.6) | *0.0248 | 65 (58.6) | *0.8092 | 13 (35.1) | *0.0194 | 131 (49.8) | *0.1812 | 107 (56.6) |
Smoker or former smoker, n (%) | 42 (38.5) | *0.1186 | 18 (40.9) | *0.1471 | 24 (36.9) | *0.2730 | 41 (41.0) | *0.0469 | 28 (84.8) | *1.98 × 10−9 | 111 (45.9) | *0.0005 | 51 (29.0) |
KL-6, U/ml (SD) | 726.6 (639.4) | 1.11 × 10−15 | 749.9 (652.6) | 1.77 × 10− 9 | 710.5 (635.1) | 3.10 × 10−12 | 383.2 (330.0) | 0.0012 | 585.5 (466.0) | 1.92 × 10−6 | 585.3 (546.4) | 2.60 × 10−13 | 293.6 (294.4) |
SP-D, ng/ml (SD) | 122.3 (144.9) | 1.95 × 10−9 | 128.6 (92.6) | 2.43 × 10− 7 | 117.9 (173.8) | 2.27 × 10−6 | 67.2 (70.9) | 0.1588 | 93.2 (69.5) | 0.0003 | 99.2 (117.4) | 4.58 × 10−7 | 51.1 (40.9) |