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Table 1 The cartilage mean volume ± standard deviation (SD), regional differences and Dice similarity coefficients between the automatic segmentation and manual correction based on automatic segmentation in different groups by articular effusion and cartilage degeneration

From: Clinical validation of the use of prototype software for automatic cartilage segmentation to quantify knee cartilage in volunteers

Sub-region ALL (n = 32) No hydrarthrosis(n = 14) Hydrarthrosis (n = 18) WORMS 0 (n = 21) WORMS 1–2 (n = 11)
mean ± SD (mL) P Dice mean ± SD (mL) P Dice mean ± SD (mL) P Dice mean ± SD (mL) P Dice mean ± SD (mL) P Dice
FMP A 0.64 ± 0.16   1.0000 0.61 ± 0.17   1.0000 0.67 ± 0.16   1.0000 0.59 ± 0.13   1.0000 0.73 ± 0.18   1.0000
M 0.64 ± 0.16 0.61 ± 0.17 0.66 ± 0.16 0.59 ± 0.13 0.73 ± 0.18
FMC A 1.08 ± 0.21 0.001 0.9978 1.02 ± 0.22 0.026 0.9975 1.12 ± 0.21 0.003 0.9979 0.99 ± 0.14 0.001 0.9971 1.25 ± 0.24 0.083 0.9992
M 1.07 ± 0.22 1.01 ± 0.22 1.12 ± 0.21 0.98 ± 0.14 1.25 ± 0.24
FMA A 0.98 ± 0.18 0.001 0.9958 0.92 ± 0.17 0.004 0.9960 1.03 ± 0.18 0.001 0.9957 0.94 ± 0.14 0.001 0.9955 1.07 ± 0.23 0.018 0.9966
M 0.97 ± 0.18 0.91 ± 0.18 1.01 ± 0.17 0.92 ± 0.14 1.06 ± 0.22
FTM A 0.90 ± 0.18 0.046 0.9994 0.86 ± 0.20 0.317 0.9993 0.93 ± 0.15 0.083 0.9995 0.86 ± 0.15 0.083 0.9992 0.98 ± 0.21 0.317 0.9999
M 0.90 ± 0.18 0.86 ± 0.20 0.93 ± 0.16 0.85 ± 0.15 0.98 ± 0.20
FTC A 1.76 ± 0.40 0.001 0.9935 1.65 ± 0.43 0.007 0.9965 1.84 ± 0.37 0.003 0.9914 1.72 ± 0.43 0.001 0.9961 1.82 ± 0.36 0.027 0.9878
M 1.73 ± 0.40 1.63 ± 0.43 1.81 ± 0.36 1.70 ± 0.43 1.78 ± 0.33
FTL A 1.76 ± 0.32 0.001 0.9945 1.63 ± 0.27 0.004 0.9930 1.86 ± 0.34 0.002 0.9956 1.67 ± 0.31 0.001 0.9943 1.92 ± 0.31 0.017 0.9951
M 1.73 ± 0.33 1.60 ± 0.29 1.84 ± 0.32 1.65 ± 0.32 1.89 ± 0.28
FLP A 0.63 ± 0.13   1.0000 0.61 ± 0.15   1.0000 0.65 ± 0.10   1.0000 0.63 ± 0.14   1.0000 0.63 ± 0.10   1.0000
M 0.63 ± 0.13 0.61 ± 0.15 0.65 ± 0.10 0.63 ± 0.14 0.63 ± 0.10
FLC A 1.06 ± 0.22 0.317 1.0000 1.00 ± 0.26   1.0000 1.11 ± 0.18 0.317 1.0000 0.97 ± 0.18 0.317 1.0000 1.23 ± 0.18   1.0000
M 1.06 ± 0.22 1.00 ± 0.26 1.11 ± 0.18 0.98 ± 0.18 1.23 ± 0.18
FLA A 1.05 ± 0.25 0.102 0.9994 0.96 ± 0.19 0.157 0.9991 1.12 ± 0.27 0.317 0.9995 0.96 ± 0.20 0.180 0.9992 1.21 ± 0.26 0.317 0.9998
M 1.05 ± 0.25 0.96 ± 0.19 1.12 ± 0.27 0.96 ± 0.20 1.21 ± 0.26
PLI A 0.26 ± 0.08 0.134 0.9860 0.23 ± 0.06 0.083 0.9902 0.28 ± 0.08 0.235 0.9831 0.25 ± 0.08 0.679 0.9830 0.27 ± 0.08 0.042 0.9927
M 0.25 ± 0.07   0.23 ± 0.07 0.27 ± 0.07 0.25 ± 0.07 0.25 ± 0.057
PLC A 0.65 ± 0.14 0.001 0.9836 0.64 ± 0.14 0.008 0.9871 0.66 ± 0.15 0.010 0.9812 0.66 ± 0.16 0.001 0.9812 0.63 ± 0.09 0.063 0.9889
M 0.64 ± 0.14 0.63 ± 0.14 0.66 ± 0.15 0.66 ± 0.17 0.63 ± 0.09
PLS A 0.19 ± 0.06   0.9932 0.17 ± 0.05   0.9923 0.21 ± 0.07   0.9938 0.19 ± 0.07   0.9917 0.17 ± 0.04   0.9964
M 0.19 ± 0.06 0.17 ± 0.05 0.21 ± 0.07 0.19 ± 0.07 0.19 ± 0.04
PMI A 0.43 ± 0.12 0.003 0.9885 0.42 ± 0.07 0.005 0.9953 0.44 ± 0.15 0.095 0.9839 0.41 ± 0.07 0.048 0.9957 0.48 ± 0.18 0.01 0.9727
M 0.42 ± 0.11 0.40 ± 0.06 0.44 ± 0.14 0.40 ± 0.06 0.46 ± 0.18
PMC A 0.94 ± 0.16 0.001 0.9923 0.94 ± 0.19 0.002 0.9925 0.94 ± 0.14 0.002 0.9921 0.95 ± 0.14 0.001 0.9913 0.91 ± 0.20 0.01 0.9945
M 0.91 ± 0.17 0.92 ± 0.19 0.91 ± 0.14 0.92 ± 0.14 0.90 ± 0.20
PMS A 0.40 ± 0.11 0.001 0.9995 0.38 ± 0.08 0.066 0.9999 0.41 ± 0.13 0.006 0.9993 0.41 ± 0.12 0.004 0.9993 0.37 ± 0.09 0.083 1.0000
M 0.39 ± 0.11 0.38 ± 0.08 0.40 ± 0.13 0.40 ± 0.11 0.36 ± 0.09
TLP A 0.84 ± 0.23 0.317 1.0000 0.79 ± 0.05 0.317 1.0000 0.87 ± 0.26   1.0000 0.79 ± 0.24 0.317 1.0000 0.92 ± 0.20   1.0000
M 0.84 ± 0.23 0.80 ± 0.05 0.87 ± 0.26 0.80 ± 0.23 0.92 ± 0.20
TLC A 1.05 ± 0.23 0.046 0.9997 1.02 ± 0.22 0.157 0.9994 1.07 ± 0.24 0.157 0.9999 1.00 ± 0.21 0.046 0.9996 1.15 ± 0.23   0.9998
M 1.05 ± 0.23 1.02 ± 0.22 1.07 ± 0.24 0.99 ± 0.22 1.15 ± 0.23
TLA A 0.52 ± 0.15 0.317 0.9998 0.48 ± 0.15   1.0000 0.55 ± 0.15 0.317 0.9997 0.49 ± 0.16   1.0000 0.58 ± 0.12 0.317 0.9994
M 0.52 ± 0.15 0.48 ± 0.15 0.55 ± 0.15 0.4895 ± 0.1614 0.58 ± 0.12
TMP A 0.52 ± 0.09 0.046 0.9993 0.52 ± 0.11 0.317 0.9994 0.52 ± 0.08 0.083 0.9991 0.5148 ± 0.0889 0.046 0.9990 0.53 ± 0.10   0.9997
M 0.52 ± 0.09 0.52 ± 0.11 0.52 ± 0.08 0.51 ± 0.09 0.53 ± 0.10
TMC A 0.85 ± 0.17 0.001 0.9972 0.82 ± 0.18 0.010 0.9974 0.87 ± 0.16 0.004 0.9971 0.80 ± 0.16 0.001 0.9970 0.93 ± 0.16 0.102 0.9978
M 0.84 ± 0.17 0.81 ± 0.18 0.86 ± 0.16 0.79 ± 0.16 0.92 ± 0.16
TMA A 0.54 ± 0.12 0.001 0.9975 0.49 ± 0.09 0.002 0.9965 0.58 ± 0.13 0.002 0.9982 0.49 ± 0.10 0.001 0.9974 0.63 ± 0.12 0.01 0.9978
M 0.52 ± 0.13 0.46 ± 0.09 0.56 ± 0.14 0.47 ± 0.10 0.62 ± 0.12
V A 17.03 ± 3.11 0.001 0.9962 16.15 ± 3.20 0.001 0.9966 17.72 ± 2.95 0.001 0.9959 16.29 ± 2.90 0.001 0.9960 18.46 ± 3.14 0.003 0.9965
M 16.87 ± 3.08 16.00 ± 3.20 17.54 ± 2.88 16.13 ± 2.91 18.29 ± 3.02
  1. Dice Dice similarity coefficient, A Automatic cartilage segmentation group, M Manual correction based on automatic segmentation group, V Volume of cartilage, FMP Femoral medial posterior, FMC Femoral medial central, FMA Femoral medial anterior, FTM Femoral trochlea medial, FTC Femoral trochlea central, FTL Femoral trochlea lateral, FLP Femoral lateral posterior, FLC Femoral lateral central, FLA Femoral lateral anterior, PLI Patellar lateral inferior, PLC Patellar lateral central, PLS Patellar lateral superior, PMI Patellar medial inferior, PMC Patellar medial central, PMS Patellar medial superior, TLP Tibial lateral posterior, TLC Tibial lateral central, TLA Tibial lateral anterior, TMP Tibial medial posterior, TMC Tibial medial central, TMA Tibial medial anterior