Table 2 The comparison of patients with or without opioid use following primary TKA
Baseline Characteristic | Opioid group, N =83 | Non-opioid group, N =278 | p |
|---|---|---|---|
Demographic characteristics | |||
Age(\(\overline{X}\)±S) | 66.1±8.9 | 66.0±7.7 | 0.897 |
Sex (male/female) | 19/64 | 45/233 | 0.160 |
BMI(\(\overline{X}\)±S, kg/m2) | 25.6±3.5 | 25.4±3.6 | 0.880 |
Diagnosis (RA/OA) | 5/78 | 8/270 | 0.177 |
Preoperative HSS | 48.7±8.9 | 49.3±8.2 | 0.582 |
Preoperative VAS | 4.9±0.7 | 4.9±0.8 | 0.578 |
Preoperative varus (N, %) | 45 (54.2%) | 149 (53.6%) | 0.921 |
Preoperative valgus (N, %) | 8 (9.6%) | 30 (10.8%) | 0.764 |
Comorbidities (N, %) | |||
Smoking | 10 (12.0%) | 17 (6.1%) | 0.071 |
Alcohol | 5 (6.0%) | 16 (5.8%) | 0.927 |
Hypertension | 48 (57.8%) | 167 (73.3%) | 0.715 |
Diabetes | 10 (12.0%) | 48 (21.1%) | 0.256 |
Coronary heart disease | 10 (12.0%) | 20 (7.2%) | 0.160 |
Preoperative anemia | 19 (22.9%) | 62 (22.3%) | 0.910 |
COPD | 8 (9.6%) | 22 (7.9%) | 0.617 |
Preoperative laboratories | |||
HB (g/L) | 131.3±13.4 | 130.7±12.9 | 0.698 |
Hct | 39.7±3.7 | 39.9±3.6 | 0.746 |
Albumin (g/L) | 42.8±3.2 | 43.4±3.2 | 0.191 |
ESR (mm/h) | 24.0±16.3 | 27.0±18.0 | 0.259 |
CRP (mg/L) | 3.5±4.28 | 3.6±3.0 | 0.748 |
IL-6 (mg/L) | 4.3±2.9 | 4.2±4.1 | 0.771 |
Platelet (*109/L) | 183.5±68.6 | 187.6±59.6 | 0.635 |
PT (sec) | 11.4±0.7 | 11.3±1.0 | 0.670 |
APTT (sec) | 27.7±3.1 | 27.5±3.3 | 0.751 |
Operative variables | |||
ASA class (N, %) | 0.789 | ||
1-2 | 70 (84.3%) | 231 (83.1%) | |
≥3 | 13 (15.7%) | 47 (16.9%) | |
Drainage use (N, %) | 22 (26.5%) | 88 (31.7%) | 0.371 |
TXA use (N, %) | 71 (85.5%) | 259 (93.2%) | 0.030* |
Dexamethasone use (N, %) | 65 (78.3%) | 234 (84.2%) | 0.214 |
Operative time (min) | 80.4±16.2 | 76.7±15.0 | 0.056 |
Intraoperative blood loss (mL) | 127.4±33.0 | 104.6±29.2 | <0.001* |