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Table 1 Demographics and Baseline BMD Values

From: Effects of secukinumab on bone mineral density and bone turnover biomarkers in patients with ankylosing spondylitis: 2-year data from a phase 3 study, MEASURE 1

Characteristic, mean (SD) unless otherwise specified

Secukinumab (N = 104)

Age (years)

40.4 (12.3)

Male, n (%)

69 (66.3)

Caucasian, n (%)

61 (58.7)

BMI (kg/m2)

26.1 (4.8)

Time since AS diagnosis (years)

6.4 (7.1)

Lumbar spine BMD (g/cm2)

1.026 (0.2)

Hip BMD (g/cm2)

0.902 (0.2)

Femoral neck BMD (g/cm2)

0.819 (0.2)

Lumbar spine BMD T-Score

−0.6 (1.6)

Hip BMD T-Score

−0.5 (1.2)

Femoral neck BMD T-Score

−0.8 (1.1)

Lumbar spine BMD Z-Score

−0.8 (1.6)

Hip BMD Z-Score

−0.6 (1.1)

Femoral neck BMD Z-Score

−0.6 (1.0)

  1. BMI body mass index, BMD bone mineral density, N number of patients with non-missing baseline BMD value and non-missing post-baseline lumbar spine BMD value at Week 52, SD standard deviation