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Table 3 Comparison of serum bone metabolism markers between SMA subtypes

From: Bone mineral density and its influencing factors in Chinese children with spinal muscular atrophy types 2 and 3

 

SMA 2a

(n = 11)

SMA 2b

(n = 11)

SMA 3a

(n = 13)

SMA 3b

(n = 5)

p-value#

Ca (mmol/L)

2.42 ± 0.07

2.47 ± 0.11

2.40 ± 0.11

2.40 ± 0.01

0.465

P (mmol/L)

1.80 ± 0.18

1.76 ± 0.17

1.79 ± 0.20

1.76 ± 0.21

0.884

ALP(U/L)

175.91 ± 52.42

151.55 ± 32.35

167.69 ± 32.71

174.40 ± 34.21

0.951

PTH (pg/ml)

23.13 ± 6.47

30.29 ± 13.59

27.95 ± 12.83

32.46 ± 7.94

0.147

25-OH-D (nmol/L)

56.77 ± 14.52

47.97 ± 14.62

59.43 ± 26.51

46.49 ± 17.81

0.559

  1. Data are shown as mean ± standard deviation. SMA spinal muscular atrophy, ALP alkaline phosphatase, PTH parathormone
  2. # p-values were calculated by Jonckheere-Terpstra test
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BMC Musculoskeletal Disorders

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