Association between sarcopenia, physical performance and falls in patients with rheumatoid arthritis: a 1-year prospective study

Wiegmann, Sabine; Armbrecht, Gabriele; Borucki, Diana; Buehring, Bjoern; Buttgereit, Frank; Detzer, Christian; Schaumburg, Désirée; Zeiner, Kim Nikola; Dietzel, Roswitha

doi:10.1186/s12891-021-04605-x

Table 3 Unadjusted and adjusted associations for fall risk

From: Association between sarcopenia, physical performance and falls in patients with rheumatoid arthritis: a 1-year prospective study

	Unadjusted						Adjusted for age and sex¹
Predictors	OR	[95% CI]	p-value	AUC	[95% CI]	p-value	OR	[95% CI]	p-value	-2 Log-Likelihood	Cox- Snell R²	Nagelkerke's R²	AUC	[95% CI]	p-value
Medical data
Age	1.04	[1.01-1.07]	0.017	0.60	[0.52-0.69]	0.026	n.a.
Sex¹	1.46	[0.64-3.36]	0.370	0.47	[0.38-0.56]	0.523	n.a.
HAQ	1.62	[1.1-2.38]	0.014	0.65	[0.57-0.73]	0.002	1.52	[1.01-2.27]	0.043	215.25	0.05	0.07	0.65	[0.56-0.74]	0.001
DAS28_CRP	1.28	[0.93-1.76]	0.125	0.57	[0.47-0.66]	0.161	1.35	[0.97-1.87]	0.072	218.65	0.04	0.07	0.64	[0.55-0.72]	0.004
RA disease duration	1.02	[0.98-1.05]	0.281	0.55	[0.45-0.64]	0.331	1.01	[0.97-1.04]	0.769	223.93	0.03	0.05	0.61	[0.53-0.7	0.014
Physical performance tests
Handgrip strength (kg)	0.97	[0.93-1.0]	0.104	0.4	[0.33-0.5]	0.063	0.98	[0.94-1.03]	0.423	230.73	0.03	0.05	0.63	[0.54-0.72]	0.006
Gait speed (m/s)	0.75	[0.18-3.17]	0.694	0.5	[0.38-0.56]	0.543	1.67	[036-7.83]	0.514	231.33	0.03	0.05	0.61	[0.53-0.7]	0.016
CRT (sec)	1.02	[0.93-1.12]	0.634	0.5	[0.43-0.62]	0.602	0.98	[0.88-1.09]	0.698	225.03	0.04	0.06	0.63	[0.54-0.72]	0.007
SPPB (score, metric)	0.97	[0.80-1.17]	0.736	0.5	[0.39-0.57]	0.666	1.10	[0.89-1.35]	0.394	231.01	0.03	0.05	0.62	[0.53-0.7]	0.014
SPPB (score, category)
Poor performer: 0-6	0.58	[0.07-4.87]	0.618	0.49	[0.40-0.58]	0.819	0.25	[0.03-2.25]	0.214	229.72	0.04	0.06	0.63	[0.53-0.72]	0.007
Moderate performer: 7-9	1.43	[0.56-3.61]	0.453				1.00	[0.38-2.65]	0.997
Good performer: 10-12	Reference						Reference
FICSIT-4 (score)
Score 1-4	2.38	[1.13-5.0]	0.022	0.43	[0.33-0.52]	0.123	1.65	[0.72-3.8]	0.239	230.41	0.04	0.06	0.62	[0.54-0.71]	0.008
Score 5	Reference			0.43	[0.33-0.52]	0.123	Reference			230.41	0.04	0.06	0.62	[0.54-0.71]	0.008
FICSIT-4 (metric)	0.74	[0.50-1.1]	0.137	0.43	[0.34-0.53]	0.150	0.94	[0.60-1.46]	0.768	231.67	0.03	0.05	0.61	[0.53-0.70]	0.015
Lean mass DXA
ASM/h² (kg/m²)	0.8	[0.57-1.08]	0.135	0.4	[0.35-0.52]	0.170	0.82	[0.56-1.21]	0.314	230.73	0.04	0.06	0.62	[0.53-0.71]	0.009
ASM/BMI (m²)	0.10	[0.01-1.29]	0.078	0.4	[0.35-0.53]	0.208	0.18	[0.0-7.13]	0.359	230.90	0.03	0.05	0.61	[0.52-0.7]	0.019
Leonardo tests
CRTP_rel (W/kg)	0.9	[0.81-1.04]	0.183	0.4	[0.35-0.54]	0.241	1	[0.87-1.14]	0.965	212.52	0.04	0.07	0.6	[0.55-0.73]	0.004
2LJP_rel (W/kg)	1	[0.90-1.0]	0.093	0.4	[0.34-0.52]	0.146	1.00	[0.94-1.07]	0.974	210.43	0.04	0.07	0.63	[0.54-0.72]	0.009
EFI (%)²	n.a.						1	[0.99-1.03]	0.387	210.30	0.04	0.07	0.5	[0.44-0.63]	0.438

¹Male = Reference
²EFI is already adjusted for age and sex

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