Thromboelastography parameters in diagnosing periprosthetic joint infection and predicting reimplantation timing

Table 3 The Diagnostic Value of Combined Inflammatory and Fibrinolytic Markers

Markers	AUC	SEN (%)	SPE (%)	PPV (%)	NPV (%)	+LR	-LR
CRP + ESR	0.980	100.00	89.47	84.6	100.0	9.50	0.000
CRP + K	0.943	91.30	94.74	91.3	94.7	17.35	0.092
CRP + Angle	0.946	91.30	94.74	91.3	94.7	17.35	0.092
CRP + MA	0.995	100.00	94.74	92.0	100.0	19.00	0.000
CRP + A30	0.999	100.00	97.37	95.8	100.0	38.00	0.000
CRP + TPI	0.968	91.30	97.37	95.5	94.9	34.70	0.089
ESR + K	0.958	86.36	94.87	90.5	92.5	16.84	0.140
ESR + Angle	0.953	86.36	94.87	90.5	92.5	16.84	0.140
ESR + MA	0.948	90.91	89.74	83.3	94.6	8.86	0.100
ESR + A30	0.948	81.82	97.44	94.7	90.5	31.91	0.190
ESR + TPI	0.955	81.82	97.44	94.7	90.5	31.91	0.190

AUC area under the curve, SEN sensitivity, SPE specificity, PPV positive predictive value, NPV negative predictive value, +LR positive likelihood ratio, −LR negative likelihood ratio, CRP C-reactive protein, K clotting time, Angle α-angle, MA maximum amplitude, A30 amplitude at 30 min, TPI thrombodynamic potential index, ESR erythrocyte sedimentation rate

ISSN: 1471-2474