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Table 2 The Diagnostic Value of Inflammatory and Fibrinolytic Markers

From: Thromboelastography parameters in diagnosing periprosthetic joint infection and predicting reimplantation timing

Markers

AUC

Optimal cutoff

Youden index

SEN (%)

SPE (%)

PPV (%)

NPV (%)

+LR

-LR

CRP (mg/L)

0.893

>8.8

0.7735

82.61

94.74

90.5

90.0

15.70

0.18

ESR (mm/h)

0.953

>34.0

0.7669

81.82

94.87

90.0

90.2

15.95

0.19

D-dimer (mg/L)

0.717

>1.7

0.4013

47.83

92.31

78.6

75.0

6.22

0.57

K (min)

0.800

<1.3

0.5362

86.96

66.67

60.6

89.7

2.61

0.20

Angle(°)

0.803

>70.7

0.5619

86.96

69.23

62.5

90.0

2.83

0.19

MA (mm)

0.895

>68.1

0.8004

82.61

97.44

95.0

90.5

32.22

0.18

A30(mm)

0.893

>66.5

0.7492

82.61

92.31

86.4

90.0

10.74

0.19

TPI(/sec)

0.867

>84.4

0.7057

78.26

92.31

85.7

87.8

10.17

0.24

  1. AUC area under the curve, SEN sensitivity, SPE specificity, PPV positive predictive value, NPV negative predictive value, +LR positive likelihood ratio, −LR negative likelihood ratio, CRP C-reactive protein, ESR erythrocyte sedimentation rate, K clotting time, Angle α-angle, MA maximum amplitude, A30 amplitude at 30 min, TPI thrombodynamic potential index