Fig. 2
From: P2Y2 promotes fibroblasts activation and skeletal muscle fibrosis through AKT, ERK, and PKC
P2Y2 promoted the proliferation of skeletal muscle fibroblasts. a Primary fibroblasts isolated from wild type or P2Y2 KO mice were cultured at 37 °C with or without TGF-β1 and assayed with cell counting kit-8 at 0, 1, 2 and 3 days. b Wild type skeletal muscle fibroblasts were treated with 10 μM PSB-1114 or 100 μM AR-C118925 for 6, 12, 24, 48, 64, and 72 h and assayed with cell counting kit-8. WT, C57Bl/6 N wild type; KO, P2Y2 knockout; PSB, PSB-1114; AR-C, AR-C118925. * p < 0.05 between specified two groups (a) or compared to wild type (b)