|
Baseline variables
|
|
Gender (female), n (%)
|
310 (74%)
|
88 (41%)
|
388 (67%)
|
P < 0.001
|
P = 0.03
|
P < 0.001
|
|
Age (years), mean ± SD
|
65.2 ± 8.4
|
62.3 ± 8.6
|
62.7 ± 8.3
|
P < 0.001
|
P < 0.001
|
P = 0.55
|
|
Radiographic severity:
|
|
K&L grade 0/1, n (%)
|
95 (24%)
|
72 (35%)
|
128 (24%)
|
P = 0.02*
|
P = 0.44
|
P < 0.001*
|
|
K&L grade 2, n (%)
|
131 (33%)
|
64 (31%)
|
145 (27%)
| | | |
|
K&L grade 3, n (%)
|
92 (23%)
|
48 (23%)
|
137 (25%)
| | | |
|
K&L grade 4, n (%)
|
83 (21%)
|
42 (12%)
|
132 (24%)
| | | |
|
Knee surgery, n (%)
|
51 (40%)
|
24 (63%)
|
65 (42%)
|
P = 0.01
|
P = 0.80
|
P = 0.02
|
|
Nr. of comorbidities:
|
|
0, n (%)
|
142 (62%)
|
97 (71%)
|
151 (43%)
|
P = 0.02
|
P < 0.001
|
P < 0.001
|
|
1, n (%)
|
61 (15%)
|
28 (21%)
|
105 (30%)
| | | |
|
2. n (%)
|
13 (3%)
|
8 (6%)
|
52 (15%)
| | | |
|
≥ 3, n (%)
|
14 (3)
|
3 (2%)
|
41 (12)
| | | |
|
Outcome variables
|
|
Knee pain (0–10), mean ± SD
|
5.6 ± 2.0
|
4.7 ± 2.2
|
5.8 ± 2.1
|
P < 0.001
|
P = 0.31
|
P < 0.001
|
|
Physical function (WOMAC, 0–68), mean ± SD
|
43.6 ± 17.3
|
30.6 ± 18.2
|
48.7 ± 18.6
|
P < 0.001
|
P < 0.001
|
P < 0.001
|
|
Stratification variables
|
|
Body mass index (kg/m2), mean ± SD
|
26.4 ± 2.5
|
25.8 ± 2.4
|
35.5 ± 5.0
|
P < 0.01
|
P < 0.001
|
P < 0.001
|
|
Quad. strength (Nm/kg), mean ± SD
|
0.71 ± 0.31
|
1.62 ± 0.32
|
0.78 ± 0.48
|
P < 0.001
|
P = 0.03
|
P < 0.001
|
|
30s-CST (repetitions), mean ± SD
|
8.5 ± 2.3
|
13.2 ± 1.2
|
9.0 ± 2.7
|
P < 0.001
|
P = 0.15
|
P < 0.001
|
