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Table 1 Demographic data

From: Safety and efficacy of single CHAP Hyaluronan injection versus three injections of linear Hyaluronan in pain relief for knee osteoarthritis: a prospective, 52-week follow-up, randomized, evaluator-blinded study

Variable

Total

(N = 140)

CHAP-HA

(N = 71)

Linear-HA

(N = 69)

Age, years (Mean ± SD)

56.3 ± 11.2

56.6 ± 12.6

56.0 ± 9.7

Age group, n (%)

  < 45 years

15 (21.1)

15 (21.1)

12 (17.4)

 45–64 years

32 (45.1)

32 (45.1)

41 (59.4)

  ≥ 65 years

24 (33.8)

24 (33.8)

16 (23.2)

Sex, n (%)

 Male

45 (32.1)

25 (35.2)

20 (29.0)

 Female

95 (67.9)

46 (64.8)

50 (71.0)

Site, n (%)

 Left

71 (50.7)

37 (52.1)

34 (49.3)

 Right

69 (49.3)

34 (47.9)

35 (50.7)

OA KL grade, n (%)

 2

106 (75.7)

52 (73.2)

54 (78.3)

 3

34 (24.3)

19 (26.8)

15 (21.7)

Work status, n (%)

 Mild

61 (43.6)

28 (39.4)

33 (47.8)

 Moderate

71 (50.7)

37 (52.1)

34 (49.3)

 Heavy

8 (5.7)

6 (8.5)

2 (2.9)

 BMI, kg/m2

25.1 ± 4.0

25.5 ± 4.2

24.7 ± 3.8

Weight status, n (%)

 Underweight

2 (1.4)

1 (1.4)

1 (1.4)

 Normal

59 (42.1)

27 (38.0)

32 (46.4)

 Overweight

39 (27.9)

22 (31.0)

17 (24.6)

 Obese

40 (28.6)

21 (29.6)

19 (27.5)

 Systolic BP (mmHg)

128.5 ± 16.7

129.5 ± 15.9

127.5 ± 17.6

 Diastolic BP (mmHg)

74.8 ± 10.6

75.0 ± 9.7

74.5 ± 11.6

 Heart rate (beat/min)

74.8 ± 9.1

74.5 ± 9.1

75.2 ± 9.1

Second injection, n (%)

 Non-injection

31 (22.1)

15 (21.1)

16 (23.2)

 Left

9 (6.4)

7 (9.9)

2 (2.9)

 Right

4 (2.9)

0 (0.0)

4 (5.8)

 Both knee

96 (68.6)

49 (69.0)

47 (68.1)

  1. OA KL: Osteoarthritis Kellgren and Lawrence grade
  2. BMI: Body Max Index
  3. BP: Blood pressure