Globulin, the albumin-to-globulin ratio, and fibrinogen perform well in the diagnosis of Periprosthetic joint infection

Table 8 Comparison of GLB, AGR, fibrinogen, ESR, and CRP between culture-positive and culture-negative PJI

Variables	Normal Rang	Culture-Positive PJI (n = 37)	Culture-Negative PJI (n = 14)	Statistics Test	P Value
GLB (g/L)^a	20–40	33.97 ± 5.53	31.23 ± 6.32	t = 1.881	0.064
AGR^a	1.2–2.4	1.09 ± 0.26	1.22 ± 0.33	t = −1.614	0.117
Fibrinogen (g/L)^a	2–4	4.52 ± 1.02	4.30 ± 0.73	t = 0.878	0.382
ESR (mm/h)^b	0–15	54.0 (46.0–64.3)	46.0 (26.0–54.0)	Z = -2.371	0.018
CRP (mg/L)^b	0–8	21.7 (13.9–35.0)	20.3 (6.5–49.2)	Z = -1.330	0.183

GLB globulin; AGR albumin-to-globulin ratio; ESR erythrocyte sedimentation rate; CRP C-reactive protein
^a The values were given as mean ± SD. SD, standard deviation
^b The values were given as median with its interquartile range (25th - 75th) in parentheses

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