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Table 2 Primary outcomes regarding VAS scores upon the movement

From: Duloxetine reduces pain after Total hip arthroplasty: a prospective, randomized controlled study

Time after surgery

Duloxetine* (n = 48)

Placebo* (n = 48)

P value†

3 h

6.0 ± 0.9

6.5 ± 1.2

0.029

6 h

5.9 ± 0.8

6.4 ± 1.0

0.016

12 h

5.4 ± 0.9

5.9 ± 1.0

0.010

24 h

5.0 ± 1.0

5.5 ± 1.2

0.033

48 h

4.4 ± 1.0

4.8 ± 1.2

0.041

72 h

3.9 ± 0.9

4.5 ± 1.1

0.004

1w

2.8 ± 1.0

3.5 ± 1.1

< 0.001

3w

1.9 ± 1.0

2.5 ± 1.1

0.007

3 m

1.6 ± 1.0

1.8 ± 1.0

0.469

  1. *The values are given as the mean and standard deviation. †P values are calculated by independent t-test. P values indicating a significant difference among groups are in bold