From: Duloxetine reduces pain after Total hip arthroplasty: a prospective, randomized controlled study
Time after surgery | Duloxetine* (n = 48) | Placebo* (n = 48) | P value† |
---|---|---|---|
3 h | 6.0 ± 0.9 | 6.5 ± 1.2 | 0.029 |
6 h | 5.9 ± 0.8 | 6.4 ± 1.0 | 0.016 |
12 h | 5.4 ± 0.9 | 5.9 ± 1.0 | 0.010 |
24 h | 5.0 ± 1.0 | 5.5 ± 1.2 | 0.033 |
48 h | 4.4 ± 1.0 | 4.8 ± 1.2 | 0.041 |
72 h | 3.9 ± 0.9 | 4.5 ± 1.1 | 0.004 |
1w | 2.8 ± 1.0 | 3.5 ± 1.1 | < 0.001 |
3w | 1.9 ± 1.0 | 2.5 ± 1.1 | 0.007 |
3 m | 1.6 ± 1.0 | 1.8 ± 1.0 | 0.469 |