Table 1 Preoperative demographics and characteristics
From: Duloxetine reduces pain after Total hip arthroplasty: a prospective, randomized controlled study
Duloxetine (n = 48) | Placebo (n = 48) | P value | |
|---|---|---|---|
Demographic data | |||
Agea (yr) | 52.7 ± 12.0 | 50.2 + 13.2 | 0.333 |
Male sexb (no.[%] of patients) | 22 (46%) | 24 (50%) | 0.683 |
BMIa (kg/m2) | 24.0 ± 2.9 | 23.9 ± 3.4 | 0.890 |
ASA statusb (no.[%] of patients) | |||
I | 8 (17%) | 4 (8%) | |
II | 28 (58%) | 32 (67%) | |
III | 12 (25%) | 12 (25%) | |
Surgical site (right/left) | 27/21 | 24/24 | |
Diagnosisb (no.of patients) | |||
Osteonecrosis of femoral head | 16 (33%) | 17 (35%) | |
Primary osteoarthritis | 15 (31%) | 13 (27%) | |
Developmental dysplasia of the hip | 9 (19%) | 10 (21%) | |
Others | 8 (17%) | 8 (17%) | |
Preoperative parametersa | |||
hip function | |||
Flexion (°) | 91.7 ± 11.8 | 90.2 ± 15.8 | 0.610 |
Abduction (°) | 21.5 ± 7.3 | 21.6 ± 8.4 | 0.948 |
Harris Hip Score (points) | 42.1 ± 9.2 | 41.2 ± 10.6 | 0.652 |
BPI-pain severity score | |||
Average | 5.4 ± 1.3 | 5.3 ± 1.1 | 0.666 |
Worst | 7.6 ± 1.4 | 7.2 ± 1.7 | 0.128 |
Least | 2.7 ± 1.2 | 2.7 ± 1.1 | 0.861 |
Current | 5.4 ± 1.6 | 5.1 ± 1.2 | 0.243 |
BPI-interference score | |||
General activity | 6.5 ± 2.0 | 6.5 ± 2.3 | 0.925 |
Walking | 7.3 ± 1.9 | 7.4 ± 2.5 | 0.853 |
Work | 6.5 ± 2.1 | 7.3 ± 2.3 | 0.082 |
Sleep | 5.0 ± 2.1 | 4.5 ± 2.3 | 0.264 |
Relations with others | 5.0 ± 2.3 | 4.7 ± 1.6 | 0.408 |
Enjoyment of life | 4.8 ± 1.5 | 4.5 ± 1.6 | 0.430 |
Mood | 5.2 ± 2.0 | 5.5 ± 2.4 | 0.512 |
HAMD | 3.3 ± 1.3 | 3.0 ± 1.4 | 0.246 |
HAMA | 3.4 ± 1.4 | 3.2 ± 1.4 | 0.425 |