From: Responsiveness of the EuroQoL 5-Dimension (EQ-5D) questionnaire in patients with spondyloarthritis
 |  | Baseline (N=151) | Follow-up Completion (N=113) | Follow-up Incompletion (N=38) | P-value |
---|---|---|---|---|---|
Demographic, % (n) | |||||
 Age, mean ± SD | 45.5±13.0 | 44.7±13.0 | 47.6±12.7 | 0.234 | |
 Gender |  |  |  | 0.145 | |
 | Female | 30.5 % (46) | 33.6 % (38) | 21.1 % (8) |  |
 | Male | 69.5 % (105) | 66.4 % (75) | 78.9 % (30) |  |
 Smoking |  |  |  |  | 0.011* |
 | Non-smoker | 81.5 % (123) | 86.7 % (98) | 65.8 % (25) |  |
 | Smoker | 9.9 % (15) | 6.2 % (7) | 21.1 % (8) |  |
 | Ex-smoker | 8.6 % (13) | 7.1 % (8) | 13.2 % (5) |  |
 Drinking |  |  |  |  | 0.732 |
 | Non-drinker | 29.3 % (44) | 30.4 % (34) | 26.3 % (10) |  |
 | Ex-drinker | 11.3 % (17) | 9.8 % (11) | 15.8 % (6) |  |
 | Social drinker | 55.3 % (83) | 55.4 % (62) | 55.3 % (21) |  |
 | Current drinker | 4.0 % (6) | 4.5 % (5) | 2.6 % (1) |  |
 Education level |  |  |  | 0.009* | |
 | Primary | 8.0 % (12) | 9.8 % (11) | 2.6 % (1) |  |
 | Secondary | 47.3 % (71) | 40.2 % (45) | 68.4 % (26) |  |
 | Tertiary or above | 44.7 % (67) | 50.0 % (56) | 29.0 % (11) |  |
 Family income level |  |  |  | 0.550 | |
 | <HK$10000 | 18.0 % (27) | 17.9 % (20) | 18.4 % (7) |  |
 | HK$10000-30000 | 43.3 % (65) | 41.1 % (46) | 50.0 % (19) |  |
 | HK$30000-60000 | 20.7 % (31) | 20.5 % (23) | 21.1 % (8) |  |
 | >HK$60000 | 18.0 % (27) | 20.5 % (23) | 10.5 % (4) |  |
 Occupation |  |  |  | 0.905 | |
 | Student | 7.3 % (11) | 8.0 % (9) | 5.3 % (2) |  |
 | Housewife | 5.3 % (8) | 4.4 % (5) | 7.9 % (3) |  |
 | Work | 72.9 % (110) | 72.6 % (82) | 73.7 % (28) |  |
 | Unemployed | 3.3 % (5) | 3.5 % (4) | 2.6 % (1) |  |
 | Retired | 11.3 % (17) | 11.5 % (13) | 10.5 % (4) |  |
Clinical, % (n) | |||||
 Positive HLA-B27 |  |  |  | 0.267 | |
 | No | 18.7 % (26) | 20.8 % (22) | 12.1 % (4) |  |
 | Yes | 81.3 % (113) | 79.2 % (84) | 87.9 % (29) |  |
 BASDAI |  |  |  | 0.588 | |
 | Low disease activity (<4) | 61.6 % (93) | 62.8 % (71) | 57.9 % (22) |  |
 | High disease activity (>=4) | 38.4 % (58) | 37.2 % (42) | 42.1 % (16) |  |
 ASDAS-CRP |  |  |  | <0.001* | |
 | Inactive disease (<1.3) | 39.7 % (60) | 47.8 % (54) | 15.8 % (6) |  |
 | Moderate disease activity (1.3-2.1) | 30.5 % (46) | 30.1 % (34) | 31.6 % (12) |  |
 | High disease activity (2.1-3.5) | 26.5 % (40) | 21.2 % (24) | 42.1 % (16) |  |
 | Very high disease activity (>3.5) | 3.3 % (5) | 0.9 % (1) | 10.5 % (4) |  |
 Family History |  |  |  |  | 0.655 |
 | No | 71.8 % (107) | 71.2 % (79) | 73.7 % (28) |  |
 | Yes | 26.8 % (40) | 27.9 % (31) | 23.7 % (9) |  |
 Axial spondyloarthritis |  |  |  |  | 0.078 |
 | No | 17.2 % (26) | 20.4 % (23) | 7.9 % (3) |  |
 | Yes | 82.8 % (125) | 79.6 % (90) | 92.1 % (35) |  |
 Peripheral spondyloarthritis |  |  |  |  | 0.030* |
 | No | 83.4 % (126) | 79.6 % (90) | 94.7 % (36) |  |
 | Yes | 16.6 % (25) | 20.4 % (23) | 5.3 % (2) |  |
 Peripheral arthritis |  |  |  | 0.093 | |
 | No | 62.3 % (94) | 58.4 % (66) | 73.7 % (28) |  |
 | Yes | 37.7 % (57) | 41.6 % (47) | 26.3 % (10) |  |
 Dactylitis |  |  |  | 0.787 | |
 | No | 96.7 % (146) | 96.5 % (109) | 97.4 % (37) |  |
 | Yes | 3.3 % (5) | 3.5 % (4) | 2.6 % (1) |  |
 Uveitis |  |  |  | 0.872 | |
 | No | 64.2 % (97) | 64.6 % (73) | 63.2 % (24) |  |
 | Yes | 35.8 % (54) | 35.4 % (40) | 36.8 % (14) |  |
 Psoriasis | |||||
 | No | 87.4 % (132) | 85.0 % (96) | 94.7 % (36) |  |
 | Yes | 12.6 % (19) | 15.0 % (17) | 5.3 % (2) |  |
 Inflammatory Bowel Disease |  |  |  |  | 0.994 |
 | No | 97.4 % (147) | 97.3 % (110) | 97.4 % (37) |  |
 | Yes | 2.6 % (4) | 2.7 % (3) | 2.6 % (1) |  |
 HADS | |||||
 | Depression |  |  |  | 0.124 |
 | Normal (0-7) | 80.6 % (112) | 79.8 % (83) | 82.9 % (29) |  |
 | Borderline (8–10) | 14.4 % (20) | 14.4 % (15) | 14.3 % (5) |  |
 | Abnormal (11–21) | 5.0 % (7) | 5.8 % (6) | 2.9 % (1) |  |
 | Anxiety |  |  |  | 0.407 |
 | Normal (0-7) | 68.4 % (95) | 71.2 % (74) | 60.0 % (21) |  |
 | Borderline (8–10) | 20.9 % (29) | 19.2 % (20) | 25.7 % (9) |  |
 | Abnormal (11–21) | 10.8 % (15) | 9.6 % (10) | 14.3 % (5) |  |
 Backpain duration |  | 16.6±12.1 | 15.9±11.5 | 17.4±12.7 | 0.540 |
 Current back pain |  |  |  |  | 0.285 |
 | No | 22.0 % (33) | 24.1 % (27) | 15.8 % (6) |  |
 | Yes | 78.0 % (117) | 75.9 % (85) | 84.2 % (32) |  |
 Tender joints |  | 0.36±1.23 | 0.40±1.36 | 0.24±0.75 | 0.488 |
 Swollen joints |  | 0.21±1.12 | 0.25±1.28 | 0.08±0.36 | 0.424 |
 Dactylitis score |  | 0.01±0.11 | 0.01±0.09 | 0.03±0.16 | 0.419 |
 Enthesitis score |  | 0.23±0.77 | 0.28±0.86 | 0.08±0.36 | 0.158 |
Baseline treatment | |||||
 NSAIDs/COX-2 Inhibitors |  |  |  |  | 0.892 |
 | No | 24.5 % (37) | 24.8 % (28) | 23.7 % (9) |  |
 | Yes | 75.5 % (114) | 75.2 % (85) | 76.3 % (29) |  |
 DMARDs |  |  |  |  | 0.041* |
 | No | 68.2 % (103) | 63.7 % (72) | 81.6 % (31) |  |
 | Yes | 31.8 % (48) | 36.3 % (41) | 18.4 % (7) |  |
 Biologics |  |  |  |  | 0.102 |
 | No | 74.2 % (112) | 70.8 % (80) | 84.2 % (32) |  |
 | Yes | 25.8 % (39) | 29.2 % (33) | 15.8 % (6) |  |
Baseline disease activity status | |||||
 | BASDAI | 3.45±1.91 | 3.43±1.90 | 3.52±1.95 | 0.793 |
 | BASFI | 2.13±1.98 | 2.09±2.06 | 2.28±1.75 | 0.610 |
 | BASMI | 4.05±1.63 | 3.98±1.56 | 4.29±1.82 | 0.309 |
 | ASDAS-ESR | 2.36±0.92 | 2.34±0.93 | 2.42±0.88 | 0.655 |
 | ASDAS-CRP | 1.63±0.98 | 1.42±0.89 | 2.26±0.98 | <0.001 |
 | CRP (g/dL) | 0.76±1.57 | 0.75±1.63 | 0.81±1.36 | 0.846 |
 | ESR (mm/hr) | 23.26±18.21 | 23.37±19.47 | 22.95±14.04 | 0.902 |
SF-36 | |||||
 | Physical functioning | 75.97±19.90 | 75.88±19.70 | 76.25±20.75 | 0.923 |
 | Role limitations due to physical functioning | 70.62±25.36 | 69.38±25.53 | 74.18±24.84 | 0.317 |
 | Bodily pain | 33.64±8.68 | 33.34±9.01 | 34.54±7.65 | 0.468 |
 | General health perceptions | 54.76±9.27 | 54.09±9.40 | 56.73±8.72 | 0.135 |
 | Vitality | 53.93±11.51 | 53.75±10.55 | 54.44±14.08 | 0.751 |
 | Role limitations due to emotional problems | 72.35±23.73 | 72.50±23.77 | 71.93±23.92 | 0.899 |
 | Social functioning | 48.92±8.92 | 47.99±8.48 | 51.64±9.71 | 0.029* |
 | Mental health | 56.17±10.62 | 56.21±10.76 | 56.05±10.34 | 0.938 |
 | Physical component summary | 38.24±7.24 | 37.97±7.27 | 39.03±7.20 | 0.696 |
 | Mental component summary | 42.76±5.34 | 42.75±5.24 | 42.77±5.71 | 0.988 |
HADS | |||||
 | Anxiety | 5.91±3.60 | 5.76±3.61 | 6.37±3.58 | 0.386 |
 | Depression | 4.81±3.46 | 4.71±3.56 | 5.11±3.17 | 0.553 |
 | Total | 10.70±6.59 | 10.43±6.68 | 11.49±6.32 | 0.415 |