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Fig. 3 | BMC Musculoskeletal Disorders

Fig. 3

From: Experimental observation of the sequence of tibial plateau chondrocyte and matrix degeneration in spontaneous osteoarthritis in Guinea pigs

Fig. 3

Proposed model for the sequence of chondrocyte and extracellular matrix degeneration. a Normal chondrocytes and normal extracellular matrix. b Degenerated chondrocytes, hypertrophic changes, and normal extracellular matrix when the OA-initiation factors appear. c Apoptosis of chondrocytes in cartilage tissue occurs,leaving empty chondrocyte lacuna. Normal extracellular matrix in cartilage tissue. d Chondrocyte degeneration and extracellular matrix degradation

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BMC Musculoskeletal Disorders

ISSN: 1471-2474

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