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Fig. 1 | BMC Musculoskeletal Disorders

Fig. 1

From: Experimental observation of the sequence of tibial plateau chondrocyte and matrix degeneration in spontaneous osteoarthritis in Guinea pigs

Fig. 1

Comparison of sequences of chondrocyte and extracellular matrix degeneration in cartilage tissue. a, b Comparisons of safranin O staining patterns of knee tibial plateau cartilage tissue and OARSI scores, IHC results of the Aggrecan,CollagenX,MMP-13 and Caspase-3 proteins and IHC scores. Comparison of serum concentration of CTX-II. Scale = 100 μm. Statistical significance is shown for One-way ANOVA. Bars represent the mean ± SEM, *p < 0.05 compared with the 8-month-old group and #p < 0.05 compared with the 10-month-old group

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