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Fig. 3 | BMC Musculoskeletal Disorders

Fig. 3

From: Cell spheroids are as effective as single cells suspensions in the treatment of critical-sized bone defects

Fig. 3

μCT-based evaluation of the defect area 6 weeks postoperatively. Representative 3D reconstruction of the defect area by high resolution μCT for MSC spheroids and suspensions (a) group. Bone volume (b) and bone mineral density (c) in the defect area as determined by μCT. Whereas no intergroup difference could be observed for bone volume, MSC spheroids group showed a significantly higher bone mineral density than the MSC suspensions group (mean ± SD; 2-sided Student’s t-test, * p < 0.05)

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