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Table 4 Changes of IL-1β, IL-18, NLRP3 and CASP1 concentration in TMJOA groups with twice HA injections

From: A comparative analysis of NLRP3-related inflammatory mediators in synovial fluid in temporomandibular joint osteoarthritis and internal derangement

 

First injection

Second injection

P

IL-1β (pg/ml)

656.50 ± 272.06

267.15 ± 159.61

< 0.001

IL-18 (pg/ml)

397.73 ± 60.03

132.06 ± 101.24

< 0.001

NLRP3 (ng/ml)

0.61 ± 0.11

0.42 ± 0.02

< 0.001

CASP1(pmol/L)

165.34 ± 29.48

169.47 ± 37.72

0.549