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Table 3 Comparison of bone mineral density between female patients in the renal tubular acidification dysfunction group and the normal function group (X±S)

From: Evaluating distal renal tubular acidification function in primary hyperparathyroidism and its effects on bone mineral density

  Distal renal tubular dysfunction group (28) Distal renal tubular normal group (26) P
Age, y 60.21 ± 13.4 57.6 ± 11.2 0.436
BMI (kg/m2) 23.82 ± 5.16 24.19 ± 3.93 0.770
Premenopausal/postmenopausal 4/24 3/23 0.112
Albumin, g/L 40.89 ± 4.11 40.50 ± 3.56 0.710
Albumin-corrected serum calcium, mmol/L 2.80 ± 0.42 2.85 ± 0.31 0.615
Serum phosphate, mmol/L 0.71 ± 0.19 0.82 ± 0.18 0.034
Serum sodium (mmol/L) 140.92 ± 3.05 141.7 ± 2.63 0.371
Serum magnesium (mmol/L) 0.81 ± 0.12 0.86 ± 0.08 0.149
PTH (pmol/L) 64.9 (25.1, 145.25) 30.15 (18.95, 65.92) 0.083 (Non-parametric)
25OHD (nmol/L) 29.5 (20.4, 41.8) 24.99 (20.23, 32.61) 0.272 (Non-parametric)
Urinary calcium, mmol/24h 8.01 ± 3.13 9.86 ± 6.21 0.169
Urinary phosphate, mmol/24h 17.84 ± 6.15 19.51 ± 8.85 0.421
Urine sodium (mmol/24h) 159.12 (97.65, 208) 187.2 (101.4, 223.0) 0.683 (Non-parametric)
Urine magnesium (mmol/24h) 3.3 (2.17, 4.06) 2.7 (2.19, 3.50) 0.486 (Non-parametric)
L1-L4 (g/cm2) 0.787 ± 0.195 0.863 ± 0.187 0.214
Femoral neck (g/cm2) 0.604 ± 0.163 0.719 ± 0.129 0.023
Total hip (g/cm2) 0.604 ± 0.159 0.756 ± 0.128 0.002
Fracture (with/without) 12/16 4/22 0.038 (Fisher)
Kidney stones (with/without) 11/17 5/21 0.107 (χ2)
Osteoporosis at any site (n,%) 19 (67%) 9 (34%) 0.015 (χ2)