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Table 3 Comparative effectiveness of intervention and placebo gloves at 12 weeks

From: Clinical and cost effectiveness of arthritis gloves in rheumatoid arthritis (A-GLOVES): randomised controlled trial with economic analysis

  Control Intervention   
Baseline
Mean (S.D.)
Control n = 103
12-week follow-up. Mean (S.D.)
Control
n = 79
Score Change
(0-12w)
Baseline
Mean (S.D.)
n = 103
12-week follow-up. Mean (S.D.)
n = 84
Score Change
(0-12w)
Adjusted between group difference e (95% CI) p-value
Dominant hand pain during activity (0–10 NRS a) 6.3 (2.2) 5.1 (2.3) 1.2 6.3 (1.9) 5.3 (2.3) 1.0 0.1 (−0.47, 0.67) 0.72
Non-dominant hand pain during activity (0–10 NRS) 5.6 (2.4) 4.5 (2.4) 1.1 5.7 (2.4) 4.3 (2.5) 1.4 −0.29 (0.94, 0.36) 0.38
Dominant hand pain during rest (0–10 NRS) 5.2 (2.4) 3.8 (2.4) 1.4 4.6 (2.2) 3.9 (2.2) 0.7 0.29 (−0.32, 0.90) 0.35
Non-dominant hand pain during rest (0–10 NRS) 4.7 (2.7) 3.6 (2.4) 1.1 4.4 (2.5) 3.3 (2.3) 1.1 −0.15 (−0.81, 0.51) 0.66
Dominant hand pain at night
(0–10 NRS)
5.5 (2.8) 3.8 (2.6) 1.4 5.0 (2.5) 4.0 (2.5) 1.4 0.34 (−0.30,0.98) 0.30
Non-dominant hand pain at night (0–10 NRS) 4.9 (2.9) 3.5 (2.7) 1.4 4.6 (2.8) 3.2 (2.5) 1.4 −0.32 (−0.98,0.35) 0.35
Hand stiffness in the morning (Minutes) 141.1 (272.8) 96.4 (226.7) 44.7 132.7 (269.8) 62.5 (53.0) 70.2 32 (−0.25,15.83) 0.37
Hand stiffness dominant hand (0–10 NRS) 6.0 (2.6) 4.9 (2.6) 1.1 5.6 (2.9) 4.9 (2.9) 0.7 0.28 (−0.41,0.97) 0.42
Hand stiffness non-dominant hand (0–10 NRS) 5.4 (2.9) 4.1 (2.7) 1.3 5.2 (2.9) 4.2 (2.9) 1.2 0.17 (−0.55,0.89) 0.64
Self-reported dominant hand condition (1–5) 3.3 (0.7) 2.9 (0.8) 0.4 3.3 (0.7) 2.8 (1.0) 0.5 −0.18 (−0.77, 0.41) 0.56
Overall MAPHAND b (Hand function) (0–3) 1.4 (0.6) 1.2 (0.6) 0.2 1.5 (0.5) 1.2 (0.6) 0.3 −0.05 (− 0.18, 0.07) 0.39
Overall HAQ c (0–3) 1.5 (0.7) 1.3 (0.7) 0.2 1.5 (0.6) 1.4 (0.8) 0.1 0 (−0.13,0.13) 0.99
Overall MHQ d (0–100) 49.8 (13.7) 57.2 (17.1) 7.4 49.3 (11.2) 57.0 (17.0) 7.9 0.37 (−3.45, 4.20) 0.85
- Overall hand function 42.8 (18.2) 50.3 (22.8) 7.5 43.6 (14.8) 54.6 (19.9) 11 3.49 (−2.05, 9.04) 0.22
- Activities of daily living 51.1. (25.8) 59.7 (27.4) 8.6 51.2 (24.0) 59.0 (27.1) 7.8 −0.69 (−6.10; 4.71) 0.80
- Work 39.5 (23.7) 50.9 (23.1) 11.4 37.7 (19.9) 48.5 (26.0) 10.8 −1.30 (−7.28, 4.69) 0.67
- Pain 35.1 (25.8) 33.6 (23.4) 1.5 32.7 (24.6) 33.1 (23.4) 0.4 −0.07 (− 6.54, 6.40) 0.98
- Aesthetics 65.5 (19.5) 69.3 (21.4) 3.8 64.2 (18.5) 66.4 (22.7) 2.2 −2.18 (−8.08, 3.72) 0.47
- Satisfaction 35.3 (21.5) 48.5 (26.6) 13.2 32.3 (16.3) 48.4 (25.4) 16.4 1.95 (−4.99, 8.90) 0.58
  1. aNRS Numeric Rating Scale, bMAPHAND Measure of Activity Performance – Hand, cHAQ Health Assessment Questionnaire, dMHQ Michigan Hand Questionnaire, eadjusted between group difference – adjusted for stratification variable (change in DMARDS) and baseline score